Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug 1;35(Suppl 2):S42-S43.
doi: 10.1097/BOT.0000000000002180.

Single-Stage Treatment of Fracture-related Infections

Olivia M Rice  1 , Kevin D Phelps  1 , Rachel Seymour  1 , Brad M Askam  2 , Laurence B Kempton  1 , Andrew Chen  3 , Scott Dart  1 , Joseph R Hsu  1
Affiliations

Single-Stage Treatment of Fracture-related Infections

Olivia M Rice et al. J Orthop Trauma. .

Abstract

Fracture-related infections (FRIs) remain a significant problem. Many approach FRI cases in a staged fashion, focusing on infection eradication initially and fracture union during subsequent procedures. The literature quotes high success rates with this strategy. However, associated patient morbidity and economic impact are noteworthy. A single-stage FRI treatment, using an antibiotic-coated locked intramedullary nail, also exists. This video details low-cost, antibiotic-coated locked intramedullary nail fabrication in the operating room alongside preliminary results using this technique for acute FRI and septic nonunion treatment.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflict of interest.

References

    1. Bezstarosti H, Van Lieshout EMM, Voskamp LW, et al. Insights into treatment and outcome of fracture-related infection: a systematic literature review. Arch Orthop Trauma Surg. 2019;139:61–72.
    1. Melvin JS, Dombroski DG, Torbert JT, et al. Open tibial shaft fractures: I. Evaluation and initial wound management. J Am Acad Orthop Surg. 2010;18:10–19.
    1. Paley D, Herzenberg JE. Intramedullary infections treated with antibiotic cement rods: preliminary results in nine cases. J Ortho Ttrauma. 2002;16:723–729.
    1. Pesch S, Hanschen M, Greve F, et al. Treatment of fracture-related infection of the lower extremity with antibiotic-eluting ceramic bone substitutes: case series of 35 patients and literature review. Infection. 2020;48:333–344.
    1. Metsemakers WJ, Smeets B, Nijs S, et al. Infection after fracture fixation of the tibia: analysis of healthcare utilization and related costs. Injury. 2017;48:1204–1210.

Publication types

Substances

LinkOut - more resources