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. 2021 Dec;185(6):1259-1262.
doi: 10.1111/bjd.20630. Epub 2021 Oct 3.

Primary cutaneous anaplastic large-cell lymphoma with marked spontaneous regression of organ manifestation after SARS-CoV-2 vaccination

T Gambichler  1 , S Boms  2 , S Hessam  2 , I Tischoff  3 , A Tannapfel  3 , T Lüttringhaus  4 , J Beckman  5 , R Stranzenbach  1
Affiliations

Primary cutaneous anaplastic large-cell lymphoma with marked spontaneous regression of organ manifestation after SARS-CoV-2 vaccination

T Gambichler et al. Br J Dermatol. 2021 Dec.
No abstract available

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Figures

Figure 1
Figure 1
(a) A male patient is shown with recurrent primary cutaneous anaplastic large‐cell lymphoma (pcALCL) on the scalp. (b) Haematoxylin & eosin histology revealed dense dermal infiltrates with large lymphocytes (scale bar = 100 µm) showing (c) strong CD30 positivity and (d) CD15 negativity on immunohistochemistry. (e) Ultrasound revealed a pathologically enlarged cervical lymph node (1 = 2·2 cm, 2 = 1·29 cm). (g) Thoracic computed tomography showed diffuse bilateral pulmonary disease with numerous tumour nodules. Shortly before treatment initiation the patient had received his first SARS‐CoV‐2 vaccination. (f) A few days later, the size of the lymph node was significantly decreased (1 = 1·23 cm, 2 = 0·71 cm) and pulmonary manifestation had almost completely spontaneously regressed (h).
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