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Review
. 2021 Aug;25(3):483-492.
doi: 10.1016/j.cld.2021.03.009. Epub 2021 May 26.

Epidemiology of Alcohol-Associated Liver Disease

Sen Han  1 , Zhihong Yang  2 , Ting Zhang  2 , Jing Ma  2 , Kristina Chandler  2 , Suthat Liangpunsakul  3
Affiliations
Review

Epidemiology of Alcohol-Associated Liver Disease

Sen Han et al. Clin Liver Dis. 2021 Aug.

Abstract

Alcohol-associated liver disease (ALD) is a consequence of excessive alcohol use. It comprises a spectrum of histopathologic changes ranging from simple steatosis, steatohepatitis, and cirrhosis to hepatocellular carcinoma. The public health impact of ALD is growing because of an increase in the prevalence and incidence of ALD in parallel with liver transplant and mortalities. There are multiple factors involved in the pathogenesis and progression of ALD. Reducing alcohol consumption is the cornerstone of ALD management. The efforts to reduce excessive alcohol use at the individual and population levels are urgently needed to prevent adverse outcomes from ALD.

Keywords: Alcoholic; Epidemiology; Liver diseases; Public health.

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Conflict of interest statement

Conflict of interest: None of the authors have any conflicts of interest relevant to this work.

Figures

Fig. 1.
Fig. 1.
The prevalence of alcohol-associated liver cirrhosis in the US population from 1998 to 2016 based on the National Health and Nutrition Examination Survey.
See this image and copyright information in PMC

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