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Practice Guideline
. 2021 Sep;74(3):1611-1644.
doi: 10.1002/hep.32049.

Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases

Jennifer C Lai #  1 , Puneeta Tandon #  2 , William Bernal  3 , Elliot B Tapper  4 , Udeme Ekong  5 , Srinivasan Dasarathy  6 , Elizabeth J Carey  7
Affiliations
Practice Guideline

Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases

Jennifer C Lai et al. Hepatology. 2021 Sep.

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] Hepatology. 2021 Dec;74(6):3563. doi: 10.1002/hep.32224. Epub 2021 Nov 11. Hepatology. 2021. PMID: 34762312 Free PMC article. No abstract available.
No abstract available

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Conflict of interest statement

Potential conflict of interest: Dr. Lai received grants from Axcella and Lipocine. Dr. Bernal advises Versantis.

Figures

FIG. 1.
FIG. 1.
Factors contributing to malnutrition, frailty, and sarcopenia and the relationship between these three constructs. Cirrhosis-related and other systems-related factors, along with physical inactivity and environmental/organizational factors, contribute to malnutrition—which then leads to frailty and sarcopenia. These factors can also contribute directly to frailty and sarcopenia independently of malnutrition.
FIG. 2.
FIG. 2.
The three levels of disease prevention and health promotion as applied to management of malnutrition, frailty, and sarcopenia in patients with cirrhosis.
FIG. 3.
FIG. 3.
Algorithm for screening, assessment, and management of malnutrition, frailty, and sarcopenia in patients with cirrhosis.
FIG. 4.
FIG. 4.
Diagnostic and management toolboxes with specific tools to facilitate diagnosis and management of malnutrition, frailty, and sarcopenia in patients with cirrhosis.
See this image and copyright information in PMC

References

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    1. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 2019;48:16–31. 10.1093/ageing/afy169. - DOI - PMC - PubMed
    1. World Health Organization. Malnutrition. https://www.who.int/health-topics/malnutrition#tab=tab_1. Accessed June 15, 2020.
    1. Bunchorntavakul C, Reddy KR. Review article: malnutrition/sarcopenia and frailty in patients with cirrhosis. Aliment Pharmacol Ther 2020;51:64–77. 10.1111/apt.15571. - DOI - PubMed

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