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Comment
. 2022 Jan;84(1):94-118.
doi: 10.1016/j.jinf.2021.07.001. Epub 2021 Jul 4.

Importance of sample dilution in the evaluation of the antibody response after SARS-CoV-2 vaccination

Julien Favresse  1 , Jonathan Douxfils  2
Affiliations
Comment

Importance of sample dilution in the evaluation of the antibody response after SARS-CoV-2 vaccination

Julien Favresse et al. J Infect. 2022 Jan.
No abstract available

Keywords: COVID-19; Dilution; SARS-CoV-2; Vaccination; mRNA vaccine.

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Figures

Fig. 1
Fig. 1
Evolution of SARS-CoV-2 spike antibodies (U/mL) in previously seronegative (blue) and seropositive individuals (red) according to the time since administration of the first vaccine dose. Means (95% confidence intervals) are shown. Three different representations according to the dilution titers applied are shown (no dilution: up to 250 U/mL; 10-fold dilution: up to 2500 U/mL; 100-fold dilution: up to 25,000 U/mL). All dilutions were automatically performed by the analyzer. Results < 0.4 U/mL (limit of quantification) were rounded to 0.4. $ = statistically different from all other groups (i.e. p <0.0001).
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