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Comment
. 2021 Jul 6;33(7):1274-1275.
doi: 10.1016/j.cmet.2021.06.008.

The therapeutic promises of NAD+ boosters

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The therapeutic promises of NAD+ boosters

Claudia Montllor-Albalate et al. Cell Metab. .
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Abstract

Numerous preclinical studies implicate the decline in NAD+ signaling in developing aging- and obesity-associated metabolic disorders. Yoshino et al. (2021) now provide the clinical evidence that an NAD+ booster increases muscle insulin sensitivity in postmenopausal prediabetic women, validating the therapeutic promises of NAD+ boosters in humans.

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Conflict of interest statement

Declaration of interests D.C. is an inventor of patents on the use of NAD boosters and sirtuin activators for stem cell aging and tissue degenerative diseases.

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