Indirect Resin Composite Inlays Cemented with a Self-adhesive, Self-etch or a Conventional Resin Cement Luting Agent: A 5 Years Prospective Clinical Evaluation

Abstract

Objective: The aim of this study was to clinically evaluate the 5-years clinical performance of indirect resin composite inlays luted with three different resin cement strategies in MOD Class II restorations.

Materials and methods: A randomized clinical trial was conducted following CONSORT guidelines. Forty patients with three large cavities indicated for indirect MOD Class II restorations were enrolled in the current study. Then, 120 indirect resin composite inlay restorations (SR Nexco) were placed and luted with three different resin cement strategies (n=40); an etch-and-rinse (Variolink N), self-etch (Panavia F2.0) and self-adhesive (RelyX Unicem). These restorations were evaluated to the periods of 1 week (baseline), 1, 3 and 5 years using modified USPHS criteria. Statistical analyses were performed with Wilcoxon and Friedman tests with level of significance set at 0.05.

Results: The outcome of the clinical trial showed that, there was neither loss of restorations nor recurrent caries after 5 years for all luting cements groups. Both self-etch Panavia F2.0 and self-adhesive RelyX Unicem resin cements exhibited significant differences between the evaluation periods regarding to marginal discoloration and marginal adaptation (p=0.03). At baseline, only 8 cases of etch-and-rinse (Variolink N) resin cement group exhibited post-operative sensitivity which were relieved after short time (p=0.04).

Conclusion: All the three resin cement strategies tested, showed acceptable clinical performance after 5-years recall period. In time, etch-and-rinse resin cement group showed better clinical performance regarding marginal discoloration and marginal adaptation at 5-years recall period. Clinical Relevance statement:In vitro and in vivo studies reveal contradictory evidence of the clinical performance of indirect resin composite inlays luted with different resin cement strategies. Thus, this study revealed that etch-and-rinse resin cement still has the best prognosis for adhesive luting of indirect resin composite inlays.

Keywords: Indirect resin composite; Inlays; Randomized clinical trial; Resin cement.