Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis

Maria Bartosova¹, Conghui Zhang¹, Betti Schaefer¹, Rebecca Herzog², David Ridinger³, Ivan Damgov¹, Eszter Levai^{1

4

5}, Iva Marinovic¹, Christoph Eckert⁶, Philipp Romero⁷, Peter Sallay⁵, Akos Ujszaszi⁸, Markus Unterwurzacher², Anja Wagner², Georg Hildenbrand³, Bradley A Warady⁹, Franz Schaefer¹, Sotirios G Zarogiannis^{1

10}, Klaus Kratochwill², Claus Peter Schmitt¹

Affiliations

¹ Center for Pediatric and Adolescent Medicine (M.B., C.Z., B.S., I.D., E.L., I.M., F.S., S.G.Z., C.P.S.), University of Heidelberg, Heidelberg, Germany.
² Christian Doppler Laboratory for Molecular Stress Research in Peritoneal Dialysis, Division of Pediatric Nephrology and Gastroenterology, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria (R.H., M.U., A.W., K.K.).
³ Kirchhoff Institute for Physics (D.R., G.H.), University of Heidelberg, Heidelberg, Germany.
⁴ ELKH-SE, Pediatrics and Nephrology Research Group, Budapest, Hungary (E.L.).
⁵ 1st Department of Pediatrics, Semmelweis University, Budapest, Hungary (E.L., P.S.).
⁶ Institute of Pathology (C.E.), University of Heidelberg, Heidelberg, Germany.
⁷ Division of Pediatric Surgery, Department of General, Visceral and Transplantation Surgery (P.R.), University of Heidelberg, Heidelberg, Germany.
⁸ Division of Nephrology, Heidelberg University Hospital, Heidelberg, Germany (A.U.).
⁹ Children's Mercy Kansas City, Kansas City, MO (B.A.W.).
¹⁰ Department of Physiology, Faculty of Medicine, University of Thessaly, Larissa, Greece (S.G.Z.).

PMID: 34233458
DOI: 10.1161/CIRCRESAHA.121.319310

Free article

Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis

Maria Bartosova et al. Circ Res. 2021.

Free article

. 2021 Aug 20;129(5):e102-e118.

doi: 10.1161/CIRCRESAHA.121.319310. Epub 2021 Jul 8.

Authors

Affiliations

¹ Center for Pediatric and Adolescent Medicine (M.B., C.Z., B.S., I.D., E.L., I.M., F.S., S.G.Z., C.P.S.), University of Heidelberg, Heidelberg, Germany.
² Christian Doppler Laboratory for Molecular Stress Research in Peritoneal Dialysis, Division of Pediatric Nephrology and Gastroenterology, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria (R.H., M.U., A.W., K.K.).
³ Kirchhoff Institute for Physics (D.R., G.H.), University of Heidelberg, Heidelberg, Germany.
⁴ ELKH-SE, Pediatrics and Nephrology Research Group, Budapest, Hungary (E.L.).
⁵ 1st Department of Pediatrics, Semmelweis University, Budapest, Hungary (E.L., P.S.).
⁶ Institute of Pathology (C.E.), University of Heidelberg, Heidelberg, Germany.
⁷ Division of Pediatric Surgery, Department of General, Visceral and Transplantation Surgery (P.R.), University of Heidelberg, Heidelberg, Germany.
⁸ Division of Nephrology, Heidelberg University Hospital, Heidelberg, Germany (A.U.).
⁹ Children's Mercy Kansas City, Kansas City, MO (B.A.W.).
¹⁰ Department of Physiology, Faculty of Medicine, University of Thessaly, Larissa, Greece (S.G.Z.).

PMID: 34233458
DOI: 10.1161/CIRCRESAHA.121.319310

Abstract

[Figure: see text].

Trial registration: ClinicalTrials.gov NCT01893710.

Keywords: apoptosis; chronic renal insufficiency; cytoskeleton; endothelium; peritoneal dialysis; proteome; vascular diseases.

PubMed Disclaimer

Comment in

GDP in Dialysis Associates With Peritoneal Vascular Remodeling in Kidney Disease.
Han Q, Orr ZJ, Desouza GK, Bagi Z, Rudic RD. Han Q, et al. Circ Res. 2021 Aug 20;129(5):527-529. doi: 10.1161/CIRCRESAHA.121.319785. Epub 2021 Aug 19. Circ Res. 2021. PMID: 34410821 Free PMC article. No abstract available.

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Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis

Affiliations

Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis

Authors

Affiliations

Abstract

Comment in

MeSH terms

Substances

Associated data

LinkOut - more resources

Full Text Sources

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Medical