Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun 30;75(6):505-507.
doi: 10.2533/chimia.2021.505.

Peptides in BioNMR Research

Oliver Zerbe  1 , Christian Baumann  2 , Matthias Schuster  2 , Kerstin Moehle  2 , Kathryn K Oi  2 , Erich Michel  2
Affiliations
Free article

Peptides in BioNMR Research

Oliver Zerbe et al. Chimia (Aarau). .
Free article

Abstract

Heteronuclear NMR in combination with isotope labelling is used to study folding of polypeptides induced by metals in the case of metallothioneins, binding of the peptidic allosteric modulator ρ-TIA to the human G-protein coupled α1b adrenergic receptor, the development of therapeutic drugs that interfere with the biosynthesis of the outer membrane of Gram-negative bacteria, and a system in which protein assembly is induced upon peptide addition. NMR in these cases is used to derive precise structural data and to study the dynamics.

PubMed Disclaimer