Prescribing Aducanumab in the Face of Meager Efficacy and Real Risks
- PMID: 34233938
- PMCID: PMC8456360
- DOI: 10.1212/WNL.0000000000012452
Prescribing Aducanumab in the Face of Meager Efficacy and Real Risks
Comment on
-
Clinical Efficacy, Drug Safety, and Surrogate Endpoints: Has Aducanumab Met All of Its Expectations?Neurology. 2021 Sep 14;97(11):517-518. doi: 10.1212/WNL.0000000000012453. Epub 2021 Jul 7. Neurology. 2021. PMID: 34233940 No abstract available.
References
-
- US Food and Drug Administration. FDA grants accelerated approval for Alzheimer’s drug. 2021. Accessed. June 7, 2021. fda.gov/news-events/press-announcements/fda-grants-accelerated-approval-...
-
- Knopman DS, Jones DT, Greicius MD. Failure to demonstrate efficacy of aducanumab: an analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019. Alzheimers Dement. 2021;17(4):696–701. - PubMed
-
- EMERGE and ENGAGE Topline Results: Two Phase 3 Studies to Evaluate Aducanumab in Patients with Early Alzheimer's Disease. 2019. Accessed December 8, 2019. investors.biogen.com/static-files/ddd45672-9c7e-4c99-8a06-3b557697c06f
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources