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Review
. 2021 Jun 28:14:2965-2973.
doi: 10.2147/IJGM.S295855. eCollection 2021.

Epidemiology and Outcomes of Status Epilepticus

Michele Ascoli  1   2 , Edoardo Ferlazzo  1   2 , Sara Gasparini  1   2 , Giovanni Mastroianni  2 , Rita Citraro  3 , Roberta Roberti  3 , Emilio Russo  3
Affiliations
Review

Epidemiology and Outcomes of Status Epilepticus

Michele Ascoli et al. Int J Gen Med. .

Abstract

Status epilepticus (SE) is a neurological and medical emergency, defined as a condition resulting either from the failure of the mechanisms responsible of seizure self-limitation or from the initiation of mechanisms which lead to atypically prolonged seizures. Further than death, SE can have long-term consequences, including neuronal injury, depending on the type, cause and duration of seizures with severe associated disabilities. In Europe, SE shows an incidence rate ranging about 9 to 40/100,000/y. In adults, mortality of patients with SE is ~30%, and even higher (up to 40%) in refractory status epilepticus. To date, etiology, duration, presence of comorbidity, level of consciousness, semiology and age are the main clinical predictors of SE outcome.

Keywords: classification; etiology; incidence; mortality; status epilepticus.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

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