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. 2021 Jun 28;5(7):e595.
doi: 10.1097/HS9.0000000000000595. eCollection 2021 Jul.

Survival in Primary Myelofibrosis: A Population-based Analysis in the Netherlands

Affiliations

Survival in Primary Myelofibrosis: A Population-based Analysis in the Netherlands

Stefanie Slot et al. Hemasphere. .
No abstract available

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Figures

Figure 1.
Figure 1.
RS of patients with primary myelofibrosis in the Netherlands. (A) and (B), RSRs according to the calendar period of diagnosis for the age categories 18–65 y (A) and >65 y (B). The tables below (A) and (B) present the projected 5- and 10-y RSR with 95% CIs. The asterisk indicates the P value for the likelihood ratio test assessing linear trends in 5-y RS from the period 2001–2010 to the period 2011–2018. (C), RS as per the IPSS risk groups, among patients diagnosed during 2014–2018. The table below (C) presents the projected 2- and 5-y RSR with 95% CI. CI = confidence interval; Int = intermediate; IPSS = International Prognostic Scoring System; RS = relative survival; RSR = relative survival rates; Unk = unknown.
Figure 2.
Figure 2.
Primary treatment of patients with primary myelofibrosis in the Netherlands. (A), Information on primary therapy (ie, initial therapy started after diagnosis, including a “wait-and-see policy”) according to age and at diagnosis and calendar period of diagnosis among patients diagnosed during 2001–2018. The absolute number and proportion of patients within a specific age group and period is shown in Supplementary Table S3 (http://links.lww.com/HS/A160). The group of other therapy encompasses immunomodulatory imide drugs, interferon-alpha, and ruxolitinib (as of 2011), among others. Of note, 6 patients with missing information on therapy were not included in this figure. (B), Specific type of primary therapy as per the IPSS risk group in the 2 age groups among patients diagnosed during 2014–2018. The absolute number and proportion of patients within a specific risk and age group is shown in Supplementary Table S5 (http://links.lww.com/HS/A160). The group of other therapy is delineated in Supplementary Table S6 (http://links.lww.com/HS/A160). alloSCT = allogeneic stem cell transplantation; Int = intermediate; IPSS = International Prognostic Scoring System.

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