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Review
. 2022 Jan;47(1):141-143.
doi: 10.1111/ced.14835. Epub 2021 Sep 2.

Vesiculobullous skin reactions induced by COVID-19 mRNA vaccine: report of four cases and review of the literature

P Coto-Segura  1 , M Fernández-Prada  2   3 , M Mir-Bonafé  1 , B García-García  1 , I González-Iglesias  4 , P Alonso-Penanes  5 , M González-Guerrero  6 , A Gutiérrez-Palacios  6 , E Miranda-Martínez  6 , F Martinón-Torres  3   7   8
Affiliations
Review

Vesiculobullous skin reactions induced by COVID-19 mRNA vaccine: report of four cases and review of the literature

P Coto-Segura et al. Clin Exp Dermatol. 2022 Jan.
No abstract available

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Figures

Figure 1
Figure 1
(a–d) Patient 2: (a,b) vesiculobullous lesions on (a) the forearms and (b) the back; (c) subepidermal blister with eosinophils in the dermis; and (d) strong positivity for C3 at the dermoepidermal junction (DEJ). (e–g) Patient 3: (e) vesiculobullous lesions on the wrist; (f) subcorneal blister with neutrophils embedded in serous transudate, with displacement over the granular layer; and (g) strong positivity for IgG at the DEJ. (h–j) Patient 4: (h) small vesicles on the thigh; (i) subepidermal bleb with eosinophils; and (j) perilesional skin with positivity for IgA at the DEJ. (c,f,i) Haematoxylin and eosin, original magnification × 200; (d,g,j) immunofluoresence, original magnification × 200.
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References

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