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. 2021 Jul 7;109(13):2041-2042.
doi: 10.1016/j.neuron.2021.06.022.

NDNF interneurons, Spartans of the cortical column: Small in number, strong in impact

Hyeyoung Shin  1 , Hillel Adesnik  2
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NDNF interneurons, Spartans of the cortical column: Small in number, strong in impact

Hyeyoung Shin et al. Neuron. .
Free article

Abstract

NDNF selectively labels neurogliaform inhibitory interneurons of layer 1. In this issue of Neuron, Cohen-Kashi Malina et al. (2021) show that NDNF activity is highly correlated with arousal level. During high arousal state, NDNF inhibits the dendrites while disinhibiting the soma of nearby pyramidal neurons.

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