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. 2021 Jun 22:11:690703.
doi: 10.3389/fonc.2021.690703. eCollection 2021.

"Fistula Zero" Project After Total Laryngectomy: The Candiolo Cancer Institute Experience

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"Fistula Zero" Project After Total Laryngectomy: The Candiolo Cancer Institute Experience

Erika Crosetti et al. Front Oncol. .

Abstract

Objectives: Pharyngocutaneous fistula (PCF) is a troublesome complication after total laryngectomy. The "Fistula zero" project aims to reduce the number of PCF by following a detailed protocol based on three fundamental key points.

Materials and methods: The Fistula zero project included 77 patients who underwent total laryngectomy in the period from January 2019 to December 2020. The protocol consisted of three main aspects: the systematic placement of a Har-El salivary bypass tube, the continuous horizontal watertight pharyngeal suture using a barbed suture, onlay insetting of a pedicled flap in pre-treated patients.

Results: One case of PCF (1.3%) and three small blind fistulas (3.9%) were observed in this series. The mean length of hospitalization was 18 days.

Conclusion: Pharyngocutaneous fistula (PCF) prolongs hospitalization and delays adjuvant treatments. Thanks to a strict adherence to the protocol, it was possible to reduce PCF rates, avoiding lengthy hospitalization and additional surgical procedures.

Keywords: Montgomery tube; bypass tube; complications; head and neck cancer; laryngeal cancer; pedicled flap; pharyngocutaneous fistula; total laryngectomy.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A) Intraoperative positioning of salivary bypass tube. (B) Naso-gastric tube (NGT) insertion inside salivary tube. (C, D) Transcutaneous securing of salivary tube. (E) Salivary stent fixation on the skin.

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References

    1. Thawley SE. Complications of Combined Radiation Therapy and Surgery for Carcinoma of the Larynx and Inferior Hypopharynx. Laryngoscope (1981) 91(5):677–700. 10.1288/00005537-198105000-00001 - DOI - PubMed
    1. Bresson K, Rasmussen H, Rasmussen PA. Pharyngo-Cutaneous Fistulae in Totally Laryngectomized Patients. J Laryngol Otol (1974) 88(9):835–42. 10.1017/s0022215100079433 - DOI - PubMed
    1. Sayles M, Grant DG. Preventing Pharyngo-Cutaneous Fistula in Total Laryngectomy: A Systematic Review and Meta-Analysis. Laryngoscope (2014) 124(5):1150–63. 10.1002/lary.24448 - DOI - PubMed
    1. Süslü N, Senirli RT, Günaydın RÖ, Özer S, Karakaya J, Hoşal AŞ. Pharyngocutaneous Fistula After Salvage Laryngectomy. Acta Otolaryngol (2015) 135(6):615–21. 10.3109/00016489.2015.1009639 - DOI - PubMed
    1. Sittitrai P, Srivanitchapoom C, Reunmakkaew D. Prevention of Pharyngocutaneous Fistula in Salvage Total Laryngectomy: Role of the Pectoralis Major Flap and Peri-Operative Management. J Laryngol Otol (2018) 132(3):246–51. 10.1017/S0022215118000178 - DOI - PubMed