Differential tolerance of thymus-independent and thymus-dependent antibody responses
- PMID: 342401
- PMCID: PMC1457698
Item in Clipboard
Differential tolerance of thymus-independent and thymus-dependent antibody responses
Immunology.
1978 Feb.
Abstract
The effect of pre-immunization with soluble haptenated serum proteins or haptenated carbohydrates on the subsequent responses to the hapten in thymus-dependent or thymus-independent form was investigated. In certain cases both thymus-dependent and -independent responses were suppressed whilst in others a differential suppression of thymus-independent responsiveness was observed. These results are discussed in terms of B-cell subpopulations and mechanisms of tolerance induction.
Similar articles
-
Genetic restrictions in the development of antibody responses to L-glutamic acid60-L-alanine30-L-tyrosine10 by nude mice implanted with semiallogeneic thymus glands.J Immunol. 1986 Feb 1;136(3):805-12. J Immunol. 1986. PMID: 2934479
-
Role of self carriers in the immune response and tolerance. X. A lymphoid dendritic-like tumor, P388AD.2, acts as a novel immunogenic carrier for hapten.J Immunol. 1986 Aug 1;137(3):777-83. J Immunol. 1986. PMID: 3522737
-
Suppression of the immune response to altered self induced by immunogenic and nonimmunogenic altered self structures.Eur J Immunol. 1980 Feb;10(2):100-4. doi: 10.1002/eji.1830100206. Eur J Immunol. 1980. PMID: 6989616
-
Induction of immunity and suppression by haptenated self structures.Immunol Rev. 1980;50:227-73. doi: 10.1111/j.1600-065x.1980.tb00313.x. Immunol Rev. 1980. PMID: 6991391 Review. No abstract available.
-
T cell-dependent suppression of an anti-hapten antibody response.Transplant Rev. 1975;26:130-69. doi: 10.1111/j.1600-065x.1975.tb00178.x. Transplant Rev. 1975. PMID: 52217 Review. No abstract available.
Cited by
-
Immunoregulation by covalent antigen-antibody complexes. II. Suppression of a T-cell independent anti-hapten response.Immunology. 1979 Oct;38(2):325-31. Immunology. 1979. PMID: 315923 Free PMC article.
-
Definition of conditions that enable antigen-specific activation of the majority of isolated trinitrophenol-binding B cells.J Exp Med. 1982 Dec 1;156(6):1635-49. doi: 10.1084/jem.156.6.1635. J Exp Med. 1982. PMID: 6184434 Free PMC article.
-
B-cell subsets responsive to fluorescein-conjugated antigens. III. Differential effect of E. Coli lipopolysaccharide on T-dependent and T-independent responses in vivo.Immunology. 1979 Nov;38(3):519-27. Immunology. 1979. PMID: 93080 Free PMC article.
-
Cyclosporin A has differential effects on the responses of murine B cells to TI antigens and B-cell mitogens.Immunology. 1986 Oct;59(2):203-7. Immunology. 1986. PMID: 2429920 Free PMC article.
-
The expression of surface IgD on B cells responsive to thymus-independent and thymus-dependent antigens and its requirement for B-cell triggering.Immunology. 1983 Feb;48(2):393-400. Immunology. 1983. PMID: 6337091 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources