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. 2021 Jul;26(27):2100626.
doi: 10.2807/1560-7917.ES.2021.26.27.2100626.

An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021

Sarah V Williams  1 , Amoolya Vusirikala  1 , Shamez N Ladhani  1 , Elena Fernandez Ruiz De Olano  2 , Nalini Iyanger  2 , Felicity Aiano  1 , Kelly Stoker  1 , Guduru Gopal Rao  3 , Laurence John  3 , Bharat Patel  1 , Nick Andrews  1 , Gavin Dabrera  1 , Mary Ramsay  1 , Kevin E Brown  1 , Jamie Lopez Bernal  1 , Vanessa Saliba  1
Affiliations

An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021

Sarah V Williams et al. Euro Surveill. 2021 Jul.

Abstract

We investigated a COVID-19 outbreak of the SARS-CoV-2 Delta variant of concern in a London care home, where 8/21 residents and 14/21 staff had received a single dose of Vaxzevria (ChAdOx1-S; AstraZeneca) vaccine. We identified 24 SARS-CoV-2 infections (16 residents, 8 staff) among 40 individuals (19 residents, 21 staff); four (3 residents, 1 staff) were hospitalised, and none died. The attack rate after one vaccine dose was 35.7% (5/14) for staff and 81.3% (13/16) for residents.

Keywords: B.1.617.2 variant; COVID-19; ChAdOx1 vaccine; Delta variant; SARS-CoV-2; Vaxzevria; care home outbreaks; vaccine effectiveness.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Epidemic curve of a COVID-19 outbreak caused by the SARS-CoV-2 Delta variant in care home residents and permanent members of staff, London, England, April 2021 (n = 24)
See this image and copyright information in PMC

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