Can children of the Sputnik V vaccine recipients become symptomatic?
- PMID: 34241575
- PMCID: PMC8290368
- DOI: 10.1080/21645515.2021.1933689
Can children of the Sputnik V vaccine recipients become symptomatic?
Abstract
Sputnik V is one of the most promising vaccines, utilizing an Adenovirus vector to cause immunity against SARS-CoV-2. Concerns existed against Adenovirus infection with this vaccine, although seemed to be a rare event. In this study, we observed that 15/18 (83%) of the children of the Sputnik V recipients became symptomatic and developed transient fever and chills for 1-2 days starting after 2-5 days following the vaccination of their parents that can be related to an Adenovirus infection. To our knowledge, this is the first study reporting such symptoms in the children of Sputnik V recipients, and the results should be validated by larger studies.
Keywords: Adverse events; COVID-19; SARS-COV-2; Sputnik V; vaccine.
References
-
- Logunov DY, Dolzhikova IV, Shcheblyakov DV, Tukhvatulin AI, Zubkova OV, Dzharullaeva AS, Kovyrshina AV, Lubenets NL, Grousova DM, Erokhova AS, et al. Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia. The Lancet. 2021;397(10275):671–81. doi:10.1016/S0140-6736(21)00234-8. - DOI - PMC - PubMed
-
- Centers for disease control and prevention, General Recommendations on Immunization, Recommendations of the Advisory Committee on Immunization Practices (ACIP), January 28, 2011. https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5515a1.html - PubMed
-
- Almuqrin A, Davidson AD, Williamson MK, Lewis P, Heesom K, Morris S, Gilbert S, Matthews DA. SARS-CoV-2 candidate vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals a normal low range of viral backbone gene expression alongside very high levels of SARS-CoV-2 S glycoprotein expression. Res Square. 2020. [published online Oct 20] (preprint). doi:10.21203/rs.3.rs-94837/v1. - DOI - PMC - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous