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Review
. 2021 Jul-Aug;29(4):262-277.
doi: 10.1097/HRP.0000000000000306.

Leveraging Systems Science to Promote the Implementation and Sustainability of Mental Health and Psychosocial Interventions in Low- and Middle-Income Countries

Affiliations
Review

Leveraging Systems Science to Promote the Implementation and Sustainability of Mental Health and Psychosocial Interventions in Low- and Middle-Income Countries

M Claire Greene et al. Harv Rev Psychiatry. 2021 Jul-Aug.

Abstract

Advancements in global mental health implementation research have revealed promising strategies for improving access to evidence-based mental health care. These advancements have not translated, however, into a reduced prevalence of mental disorders. In this review we examine the relationships between determinants (i.e., barriers and facilitators) and outcomes of mental health services in low- and middle-income countries to identify opportunities for improving the population-level impact and sustainability of innovations in global mental health. We identified three key implementation and services outcomes that influenced the prevalence of mental disorders in the 56 included review articles: supply (access, implementation), demand (help seeking, utilization), and quality (effectiveness, quality of care) of mental health services. Determinants of these outcomes revealed seven themes: community stakeholder engagement; cultural relevance; stigma; human resource capacity; organization of services; governance, policy, and financing; and sociopolitical and community context. We developed a causal loop diagram to illustrate the relationships among these determinants and outcomes. The causal loop diagram revealed the central role of community stakeholder engagement in bridging implementation and patient outcomes, the importance of addressing stigma and social determinants of mental health, and the need to complement supply-side implementation strategies with approaches to equilibrate demand and improve the quality of services. Applying systems science methodologies to global mental health research presents an opportunity to examine the complex relationships among community and health system factors that influence implementation of evidence-based interventions in order to identify sustainable approaches to improve the population-level impact of mental health services in low- and middle-income countries.

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Conflict of interest statement

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Figures

Figure 1.
Figure 1.
Common barriers and facilitators of implementing and sustaining mental health services in low- and middle-income countries across social-ecological levels. Adapted from Proctor et al. (2011) and Shelton et al. (2018).
Figure 2.
Figure 2.
Factors contributing to the implementation and sustainability of mental health services and the prevalence of mental disorders in low- and middle-income countries. Reinforcing loop (R): amplifying processes whereby changes in the determinants and outcomes described in the loop result in an exponential growth or decline unless regulated by external forces. Balancing loop (B): self-regulating processes that limit growth or maintain equilibrium of a process leading to a plateau or steady state over time. Positive association (+): higher levels of determinant lead to higher levels of outcome; lower levels of determinant lead to lower levels of outcome. Negative association (−): higher levels of determinant lead to lower levels of outcome; lower levels of determinant lead to higher levels of outcome. A larger, full-color version of this figure is available online as Supplemental Figure 4, http//1inks.lww.com/HRP/A178.

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References

    1. Global Burden of Disease Injury Incidence Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018;392:1789–858. - PMC - PubMed
    1. Steel Z, Marnane C, Iranpour C, et al. The global prevalence of common mental disorders: a systematic review and meta-analysis 1980–2013. Int J Epidemiol 2014;43:476–93. - PMC - PubMed
    1. Kohn R, Saxena S, Levav I, Saraceno B. The treatment gap in mental health care. Bull World Health Organ 2004;82:858–66. - PMC - PubMed
    1. Wang PS, Aguilar-Gaxiola S, Alonson J, et al. Use of mental health services for anxiety, mood, and substance disorders in 17 countries in the WHO world mental health surveys. Lancet 2007;370:841–50. - PMC - PubMed
    1. Betancourt TS, Chambers DA. Optimizing an era of global mental health implementation science. JAMA Psychiatry 2016;73: 99–100. - PubMed

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