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Comment
. 2021 Aug 17;144(7):1941-1942.
doi: 10.1093/brain/awab247.

Distinct cardiac-locked brain pulsations in Alzheimer's disease

Sydney M Bailes  1 , Laura D Lewis  1
Affiliations
Comment

Distinct cardiac-locked brain pulsations in Alzheimer's disease

Sydney M Bailes et al. Brain. .

Abstract

This scientific commentary refers to ‘Cardiovascular brain impulses in Alzheimer’s disease’ by Rajna et al. (doi:10.1093/brain/awab144).

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Figures

Figure 1
Figure 1
Schematic overview of propagation of cardiovascular brain pulsations. (A) Illustration of the typical path of cardiovascular pulse propagation through the brain. (B) Example illustration of voxel-wise measurements of optical flow vector (v), and calculations of speed and direction.
See this image and copyright information in PMC

Comment on

  • Cardiovascular brain impulses in Alzheimer's disease.
    Rajna Z, Mattila H, Huotari N, Tuovinen T, Krüger J, Holst SC, Korhonen V, Remes AM, Seppänen T, Hennig J, Nedergaard M, Kiviniemi V. Rajna Z, et al. Brain. 2021 Aug 17;144(7):2214-2226. doi: 10.1093/brain/awab144. Brain. 2021. PMID: 33787890 Free PMC article.

References

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    1. Mestre H, Tithof J, Du T, et al.Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension. Nat Commun. 2018;9(1):4878. - PMC - PubMed
    1. Rajna Z, Mattila H, Huotari N, et al.Cardiovascular brain impulses in Alzheimer’s disease. Brain. 2021;144(7):2214–2226. - PMC - PubMed

Publication types