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. 2021 Sep;21 Suppl 3(Suppl 3):1-16.
doi: 10.1111/ajt.16738. Epub 2021 Jul 29.

First world consensus conference on pancreas transplantation: Part I-Methods and results of literature search

Ugo Boggi  1 , Fabio Vistoli  1 , Piero Marchetti  2 , Raja Kandaswamy  3 , Thierry Berney  4 ; World Consensus Group on Pancreas Transplantation
Collaborators, Affiliations

First world consensus conference on pancreas transplantation: Part I-Methods and results of literature search

Ugo Boggi et al. Am J Transplant. 2021 Sep.

Abstract

Comprehensive evidence-based guidelines for the practice of pancreas transplantation are yet to be established. The First World Consensus Conference on Pancreas Transplantation was convened for this purpose. A steering committee selected the participants and defined the questions to be addressed. A group of literature reviewers identified 597 studies to be included in summaries for guidelines production. Expert groups formulated the first draft of recommendations. Two rounds of discussion and voting occurred online, using the Delphi method (agreement rate ≥85%). After each round, critical responses of experts were reviewed, and recommendations were amended accordingly. Recommendations were finalized after live discussions. Each session was preceded by expert presentations and a summary of results of systematic literature review. Up to three voting rounds were allowed for each recommendation. To avoid potential conflicts of interest, deliberations on issues regarding the impact of pancreas transplantation on the management of diabetes were conducted by an independent jury. Recommendations on technical issues were determined by experts and validated using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument. Quality of evidence was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) methodology. Each recommendation received a GRADE rating (Grading of Recommendations, Assessment, Development and Evaluations).

Keywords: clinical research / practice; diabetes; pancreas / simultaneous pancreas-kidney transplantation; survey.

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Conflict of interest statement

The authors of this manuscript have no conflicts of interest to disclose as described by the American Journal of Transplantation.

Figures

FIGURE 1
FIGURE 1
Flow chart of guideline process
FIGURE 2
FIGURE 2
Flow chart of literature reviews
See this image and copyright information in PMC

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