Multisystem Inflammatory Syndrome in Children
- PMID: 34248441
- PMCID: PMC8258545
- DOI: 10.1016/j.nurpra.2021.05.008
Multisystem Inflammatory Syndrome in Children
Abstract
Multisystem inflammatory syndrome in children (MIS-C), which was first documented in the United Kingdom and later recognized in other countries, is a postinfectious immune response to coronavirus disease 2019 (COVID-19). Its clinical manifestation resembles that of other inflammatory processes. Differentiation can be accomplished through epidemiology, a positive temporal relationship to COVID-19, and multiorgan involvement. Health care providers should maintain a high level of suspicion for MIS-C during the COVID-19 pandemic. A consistent picture of this immune response is emerging and diagnostic and treatment approaches are evolving. Advances continue to be made in the knowledge attainment regarding MIS-C clinical presentation and management.
Keywords: MIS-C; children; immune response; inflammatory.
© 2021 Elsevier Inc. All rights reserved.
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