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Review
. 2021 Jul 1;4(3):e318.
doi: 10.1002/hsr2.318. eCollection 2021 Sep.

Re-evaluating expanding intravenous catheters in medical practice

Rigoberto Vazquez  1 , Rishabh Tennankore  2 , Ariella Shikanov  3 , Leonard A Mermel  4   5 , Brian Love  2   3 , Michael L Burns  6
Affiliations
Review

Re-evaluating expanding intravenous catheters in medical practice

Rigoberto Vazquez et al. Health Sci Rep. .

Abstract

Background: Intravenous catheters are common and essential devices within medical practice. Their placement can be difficult, leading to application of several technologies to improve success. Functionally expanding catheters were once an exciting technology, derailed clinically by hypersensitivity reactions. The exact cause of reactions, attributed to Aquavene catheter materials, remains unknown.

Aims: To reinvestigate functionally expanding intravenous catheters.

Materials and methods: The history of the functionally expanding intravenous catheter is presented here along with its utility in current medical practice, potential for further investigation, and possible redesign of these once promising devices.

Results: This review demonstrates clinical utility and a lack of definitive cause for failure of the previous functionally expanding intravenous catheter design. As Aquavene materials themselves are commonly considered the cause of hypersensitivity reactions which removed expanding intravenous catheters from the market, this review found several possible substitutes for this material for use in any redesign.

Discussion and conclusion: The functionally expanding intravenous catheter failed due to hypersensitivity reactions in patients. Alternative materials exist for a possible redesign on this once promising clinical product.

Keywords: Aquavene; UV cross‐linking; anaphylactoid reaction; biopolymer; heterogeneous network; intravenous catheter; poly(ethylene glycol).

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
In vitro catheter flow over time comparing Menlo Care 20‐gauge IV catheter (Menlo 20) with four common Teflon catheters. Each point represents the average of three catheters (Fig. 1 from the ASA abstract 5 : Reprinted with permission from the American Society of Anesthesiologists)
See this image and copyright information in PMC

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