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Editorial
. 2021 Oct 1;23(10):1627-1628.
doi: 10.1093/neuonc/noab164.

Selumetinib for optic pathway glioma: Seeing through the fog, (not yet) the end of the tunnel?

Vijay Ramaswamy  1 , Ute Bartels  1
Affiliations
Editorial

Selumetinib for optic pathway glioma: Seeing through the fog, (not yet) the end of the tunnel?

Vijay Ramaswamy et al. Neuro Oncol. .
No abstract available

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References

    1. Jones DTW, Kieran MW, Bouffet E, et al. . Pediatric low-grade gliomas: next biologically driven steps. Neuro Oncol. 2018;20(2):160–173. - PMC - PubMed
    1. Krishnatry R, Zhukova N, Guerreiro Stucklin AS, et al. . Clinical and treatment factors determining long-term outcomes for adult survivors of childhood low-grade glioma: a population-based study. Cancer. 2016;122(8):1261–1269. - PubMed
    1. Fangusaro J, Onar-Thomas A, Young Poussaint T, et al. . Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial. Lancet Oncol. 2019;20(7):1011–1022. - PMC - PubMed
    1. Banerjee A, Jakacki RI, Onar-Thomas A, et al. . A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study. Neuro Oncol. 2017;19(8):1135–1144. - PMC - PubMed
    1. Fangusaro J, Onar-Thomas A, Poussaint TY, et al. . A phase 2 trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a pediatric brain tumor consortium study. Neuro Oncol. 2021;23(10):1777–1788. - PMC - PubMed