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Review
. 2021 Sep;45(2-3):75-86.
doi: 10.1007/s11259-021-09808-0. Epub 2021 Jul 12.

Porcine enteric coronaviruses: an updated overview of the pathogenesis, prevalence, and diagnosis

Qiang Liu  1 , Huai-Yu Wang  2
Affiliations
Review

Porcine enteric coronaviruses: an updated overview of the pathogenesis, prevalence, and diagnosis

Qiang Liu et al. Vet Res Commun. 2021 Sep.

Abstract

The recent prevalence of coronavirus (CoV) poses a serious threat to animal and human health. Currently, porcine enteric coronaviruses (PECs), including the transmissible gastroenteritis virus (TGEV), the novel emerging swine acute diarrhoea syndrome coronavirus (SADS-CoV), porcine delta coronavirus (PDCoV), and re-emerging porcine epidemic diarrhoea virus (PEDV), which infect pigs of different ages, have caused more frequent occurrences of diarrhoea, vomiting, and dehydration with high morbidity and mortality in piglets. PECs have the potential for cross-species transmission and are causing huge economic losses in the pig industry in China and the world, which therefore needs to be urgently addressed. Accordingly, this article summarises the pathogenicity, prevalence, and diagnostic methods of PECs and provides an important reference for their improved diagnosis, prevention, and control.

Keywords: Porcine delta coronavirus; Porcine enteric coronavirus; Porcine epidemic diarrhoea virus; Swine acute diarrhoea syndrome coronavirus; Transmissible gastroenteritis virus.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Fig. 1
Fig. 1
Genomic structures of porcine enteric coronavirus, including TGEV (A), PEDV (B), SADS-CoV (C), and PDCoV (D). Viral structural genes and presumed accessory genes are shown. There are 5′-terminal cap structures and 3′-terminal poly (A) tails at both ends of the genome. TGEV, transmissible gastroenteritis virus; SADS-CoV, swine acute diarrhoea syndrome coronavirus; PDCoV, porcine delta coronavirus; PEDV, porcine epidemic diarrhoea virus
See this image and copyright information in PMC

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