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. 2021:2328:139-151.
doi: 10.1007/978-1-0716-1534-8_8.

Biological Network Mining

Zongliang Yue  1 , Da Yan  2 , Guimu Guo  1 , Jake Y Chen  1
Affiliations

Biological Network Mining

Zongliang Yue et al. Methods Mol Biol. 2021.

Abstract

In this book chapter, we introduce a pipeline to mine significant biomedical entities (or bioentities) in biological networks. Our focus is on prioritizing both bioentities themselves and the associations between bioentities in order to reveal their biological functions. We will introduce three tools BEERE, WIPER, and PAGER 2.0 that can be used together for network analysis and function interpretation: (1) BEERE is a network analysis tool for "Biomedical Entity Expansion, Ranking and Explorations," (2) WIPER is an entity-to-entity association ranking tool, and (3) PAGER 2.0 is a service for gene enrichment analysis.

Keywords: Gene; Microarray; Network mining; Protein; Protein–protein interaction (PPI).

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