Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun 28:2021:1093412.
doi: 10.1155/2021/1093412. eCollection 2021.

Central Odontogenic Myxoma: A Radiographic Analysis

Ahmad Badruddin Ghazali  1 , Raweewan Arayasantiparb  1 , Rachai Juengsomjit  2 , Aroonwan Lam-Ubol  3
Affiliations

Central Odontogenic Myxoma: A Radiographic Analysis

Ahmad Badruddin Ghazali et al. Int J Dent. .

Abstract

Objective: This study aimed to determine the radiographic characteristics of odontogenic myxomas (OMs) and their associations.

Materials and methods: The study enrolled radiographs of patients taken between 2005 and 2019 with a confirmed histopathological diagnosis of central OM. OM radiographic features were evaluated, including location, border, locularity, involved area, the number of included teeth, root resorption, tooth displacement, bone expansion, bone perforation, and periosteal reaction. Fisher's exact test was used for statistical analysis.

Results: Significant associations were found between the OM border and the affected jaw (p=0.036), locularity (p=0.036), involved areas (p=0.009), and bone perforation (p=0.036). OMs with an ill-defined border were associated with maxillary lesions, multilocularity, dentate areas, and cortical bone perforation. The number of included teeth (2 or fewer or 3 or more) was significantly associated with locularity (p=0.010), involved area (p=0.045), and bone expansion (p=0.010). Larger OMs including 3 or more teeth, were associated with a multilocular appearance, dentate areas, and bone expansion.

Conclusion: The border of OM and the number of included teeth are related to other radiographic appearances. Understanding these relationships could help in treatment decisions and help better understand the nature of OM.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Maxillary odontogenic myxoma in a 26-year-old woman (Patient 3). Cropped panoramic image shows ill-defined multilocular radiolucency located in the dentate area from maxillary right first premolar to the third molar.
Figure 2
Figure 2
Mandibular odontogenic myxoma in a 44-year-old woman (Patient 9). Cropped panoramic image shows well-defined corticated, unilocular radiolucency associated with unerupted mandibular right third molar.
Figure 3
Figure 3
Axial CBCT images. (a) Maxillary odontogenic myxoma (Patient 3) at the dentate area, including more than 3 teeth with bone expansion and perforation (arrows). (b) Mandibular odontogenic myxoma (Patient 9) with unerupted third molar without bone perforation.
See this image and copyright information in PMC

References

    1. Odell E. W., Adebiyi K. Benign mesenchymal odontogenic tumours. In: EI-Maggar A. K., Chan J. K. C., Grandis J. R., Takata T., Slootweg P. J., editors. WHO Classification of Head and Neck Tumours. 4th. Lyon, France: IARC; 2017. pp. 229–230.
    1. Simon E. N. M., Merkx M. A. W., Vuhahula E., Ngassapa D., Stoelinga P. J. W. Odontogenic myxoma: a clinicopathological study of 33 cases. International Journal of Oral and Maxillofacial Surgery. 2004;33(4):333–337. doi: 10.1016/j.ijom.2003.12.004. - DOI - PubMed
    1. Siriwardena B. S. M. S., Crane H., O’Neill N., et al. Odontogenic tumors and lesions treated in a single specialist oral and maxillofacial pathology unit in the United Kingdom in 1992-2016. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2019;127(2):151–166. doi: 10.1016/j.oooo.2018.09.011. - DOI - PubMed
    1. Hosgor H., Tokuc B., Kan B., Coskunses F. M. Evaluation of biopsies of oral and maxillofacial lesions: a retrospective study. Journal of the Korean Association of Oral and Maxillofacial Surgeons. 2019;45(6):316–323. doi: 10.5125/jkaoms.2019.45.6.316. - DOI - PMC - PubMed
    1. Takahashi Y., Tanaka K., Hirai H., Marukawa E., Izumo T., Harada H. Appropriate surgical margin for odontogenic myxoma: a review of 12 cases. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2018;126(5):404–408. doi: 10.1016/j.oooo.2018.06.002. - DOI - PubMed

LinkOut - more resources