Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jul 6;9(7):e04409.
doi: 10.1002/ccr3.4409. eCollection 2021 Jul.

Post-COVID worsening of a Parkinson's disease patient

Affiliations
Case Reports

Post-COVID worsening of a Parkinson's disease patient

Aliaksandr V Boika et al. Clin Case Rep. .

Abstract

Worsening of clinical symptoms after COVID-19 infection and misregulation of CD4 and CD8 T-cell numbers may be revealed in PD patients. Immunological changes may be a source of clinical worsening of the patient.

Keywords: Parkinson's disease; Post‐COVID‐19; immunology; motor symptoms; nonmotor symptoms.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Henry J, Smeyne R, Jang H, et al. Parkinsonism and neurological manifestations of influenza throughout the 20th and 21st centuries. Parkinsonism Relat Disord. 2010;16:566‐571. - PMC - PubMed
    1. Pinto LH, Lamb RA. Understanding the mechanism of action of the anti‐influenza virus drug amantadine. Trends Microbiol. 1995;3:271. - PubMed
    1. Cilia R, Bonvegna S, Straccia G, et al. Effects of COVID‐19 on Parkinson's disease clinical features: a community‐based case‐control study. Mov Disord. 2020. 10.1002/mds.28170 - DOI - PMC - PubMed
    1. Chen G, Wu D, Guo W, et al. Clinical and immunological features of severe and moderate coronavirus disease 2019. J Clin Invest. 2020;130(5):2620‐2629. 10.1172/JCI137244 - DOI - PMC - PubMed
    1. Nie S, Zhao X, Zhao K, Zhang Z, Zhang Z, Zhang Z. Metabolic disturbances and inflammatory dysfunction predict severity of coronavirus disease 2019 (COVID‐19): a retrospective study. medRxiv. 2020. 10.1101/2020.03.24.20042283 - DOI

Publication types