Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jun 22:25:e01204.
doi: 10.1016/j.idcr.2021.e01204. eCollection 2021.

Granulicatella adiacens: An uncommon diagnosis of prosthetic hip joint infection. A case report with review of the literature

Affiliations
Case Reports

Granulicatella adiacens: An uncommon diagnosis of prosthetic hip joint infection. A case report with review of the literature

Timothy C Badrick et al. IDCases. .

Abstract

We report a case of prosthetic hip infection in a 79 year old man caused by Granulicatella adiacens. The diagnosis was achieved using broad range 16S PCR gene analysis at an early stage, after joint aspiration and culture failed to yield a pathogen. Staged revision surgery together with administration of appropriate antibiotics resulted in cure. Granulicatella adiacens is a nutritionally variant streptococcus (NVS). It has been increasingly reported to cause significant morbidities involving various systems. Its insidious growth due to complex growth requirements, has made its diagnosis challenging, and often delays appropriate antibiotic administration.

Keywords: 16S PCR; Challenging diagnosis; Granulicatella adiacens; Prosthetic hip infection.

PubMed Disclaimer

Conflict of interest statement

The authors report no declarations of interest.

References

    1. Collins M.D., Lawson P.A. The genus Abiotrophia (Kawamura et al.) is not monophyletic: Proposal of Granulicatella gen. nov., Granulicatella adiacens comb. nov., Granulicatella elegans comb. nov. and Granulicatella balaenopterae comb. nov. Int J Syst Evol Microbiol. 2000 doi: 10.1099/00207713-50-1-365. - DOI - PubMed
    1. Frenkel A., Hirsch W. Spontaneous development of L forms of streptococci requiring secretions of other bacteria or sulphydryl compounds for normal growth. Nature. 1961 doi: 10.1038/191728a0. - DOI - PubMed
    1. Carlier J.P., Bouvet A. Fermentation products of nutritionally variant streptococci: additional evidence for their classification in the genus streptococcus. Res Microbiol. 1989 doi: 10.1016/0923-2508(89)90045-4. - DOI - PubMed
    1. Kawamura Y., Hou X.G., Sultana F., Liu S., Yamamoto H., Ezaki T. Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adjacens comb. nov. and Abiotrophia defectiva comb. nov., respectively. Int J Syst Bacteriol. 1995 doi: 10.1099/00207713-45-4-798. - DOI - PubMed
    1. Aweid O., Sundararajan S., Teferi A. Granulicatella adiacens prosthetic hip joint infection after dental treatment. JMM Case Rep. 2016 doi: 10.1099/jmmcr.0.005044. - DOI - PMC - PubMed

Publication types

LinkOut - more resources