Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jun 3:14:10-12.
doi: 10.1016/j.jdcr.2021.05.028. eCollection 2021 Aug.

Subacute cutaneous lupus erythematosus following abemaciclib therapy for metastatic breast cancer

David J Kurtyka  1 , Aurash David Mohebbi  1 , Katherine T Burke  1   2 , Michael A Cardis  1   2
Affiliations
Case Reports

Subacute cutaneous lupus erythematosus following abemaciclib therapy for metastatic breast cancer

David J Kurtyka et al. JAAD Case Rep. .
No abstract available

Keywords: CDK, cyclin-dependent kinase; CDK4/6 inhibitors; SCLE, subacute cutaneous lupus erythematosus; SLE, systemic lupus erythematosus; cutaneous drug reactions; lupus; metastatic breast cancer treatment; subacute cutaneous lupus erythematosus.

PubMed Disclaimer

Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Physical examination. A, Annular pink thin scaly plaques on the chest and dorsal extremities. B, Pink to red scaly papules and plaques in the central and upper portion of the back.
Fig 2
Fig 2
Histopathology. A, Vacuolar changes of basal keratinocytes, focal epidermal atrophy, dyskeratotic keratinocytes, and a moderately dense superficial and deep perivascular and periadnexal infiltrate, with an increase in interstitial mucin. B, Focal epidermal atrophy, basilar vacuolization, and dyskeratotic keratinocytes. (Original magnifications: A, ×100; B, ×400.)
See this image and copyright information in PMC

References

    1. Reed B.R., Huff J.C., Jones S.K., Orton P.W., Lee L.A., Norris D.A. Subacute cutaneous lupus erythematosus associated with hydrochlorothiazide therapy. Ann Intern Med. 1985;103(1):49–51. - PubMed
    1. Lowe G.C., Henderson C.L., Grau R.H., Hansen C.B., Sontheimer R.D. A systematic review of drug-induced subacute cutaneous lupus erythematosus. Br J Dermatol. 2011;164(3):465–472. - PubMed
    1. Grönhagen C.M., Fored C.M., Linder M., Granath F., Nyberg F. Subacute cutaneous lupus erythematosus and its association with drugs: a population-based matched case-control study of 234 patients in Sweden. Br J Dermatol. 2012;167(2):296–305. - PubMed
    1. Floristan U., Feltes R.A., Sendagorta E. Subacute cutaneous lupus erythematosus induced by capecitabine. Clin Exp Dermatol. 2009;34(7):e328–e329. - PubMed
    1. Beaver J.A., Amiri-Kordestani L., Charlab R. FDA approval: palbociclib for the treatment of postmenopausal patients with estrogen receptor-positive, HER2-negative metastatic breast cancer. Clin Cancer Res. 2015;21(21):4760–4766. - PubMed

Publication types

LinkOut - more resources