Value of PET imaging for radiation therapy

Constantin Lapa¹, Ursula Nestle^{2

3

4}, Nathalie L Albert⁵, Christian Baues⁶, Ambros Beer⁷, Andreas Buck⁸, Volker Budach⁹, Rebecca Bütof^{10

11}, Stephanie E Combs^{12

13

14}, Thorsten Derlin¹⁵, Matthias Eiber¹⁶, Wolfgang P Fendler¹⁷, Christian Furth¹⁸, Cihan Gani^{19

20}, Eleni Gkika², Anca-L Grosu^{2

3}, Christoph Henkenberens²¹, Harun Ilhan⁵, Steffen Löck^{10

11}, Simone Marnitz-Schulze⁶, Matthias Miederer²², Michael Mix²³, Nils H Nicolay^{2

3}, Maximilian Niyazi^{5

12}, Christoph Pöttgen²⁴, Claus M Rödel^{25

26}, Imke Schatka¹⁸, Sarah M Schwarzenboeck²⁷, Andrei S Todica⁵, Wolfgang Weber¹⁶, Simone Wegen⁶, Thomas Wiegel²⁸, Constantinos Zamboglou^{2

3}, Daniel Zips^{19

20}, Klaus Zöphel^{11

29

30

31

32}, Sebastian Zschaeck³³, Daniela Thorwarth^{19

34}, Esther G C Troost^{35

36

37

38

39}; Arbeitsgemeinschaft Nuklearmedizin und Strahlentherapie der DEGRO und DGN

Collaborators, Affiliations

Collaborators

Arbeitsgemeinschaft Nuklearmedizin und Strahlentherapie der DEGRO und DGN:
Constantin Lapa, Ursula Nestle, Nathalie L Albert, Christian Baues, Ambros Beer, Andreas Buck, Volker Budach, Rebecca Bütof, Stephanie E Combs, Thorsten Derlin, Matthias Eiber, Wolfgang P Fendler, Christian Furth, Cihan Gani, Eleni Gkika, Anca-L Grosu, Christoph Henkenberens, Harun Ilhan, Steffen Löck, Simone Marnitz-Schulze, Matthias Miederer, Michael Mix, Nils H Nicolay, Maximilian Niyazi, Christoph Pöttgen, Claus M Rödel, Imke Schatka, Sarah M Schwarzenboeck, Andrei S Todica, Wolfgang Weber, Simone Wegen, Thomas Wiegel, Constantinos Zamboglou, Daniel Zips, Klaus Zöphel, Sebastian Zschaeck, Daniela Thorwarth, Esther G C Troost

Affiliations

¹ Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany.
² Department of Radiation Oncology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.
³ German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
⁴ Department of Radiation Oncology, Kliniken Maria Hilf, Mönchengladbach, Germany.
⁵ Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.
⁶ Department of Radiation Oncology, Cyberknife and Radiotherapy, Medical Faculty, University Hospital Cologne, Cologne, Germany.
⁷ Department of Nuclear Medicine, Ulm University Hospital, Ulm, Germany.
⁸ Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
⁹ Department of Radiation Oncology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.
¹⁰ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
¹¹ OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.
¹² German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.
¹³ Department of Radiation Oncology, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
¹⁴ Department of Radiation Sciences (DRS), Institute of Radiation Medicine (IRM), Neuherberg, Germany.
¹⁵ Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
¹⁶ Department of Nuclear Medicine, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
¹⁷ Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
¹⁸ Department of Nuclear Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
¹⁹ German Cancer Consortium (DKTK), Partner Site Tübingen, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
²⁰ Department of Radiation Oncology, University of Tübingen, Tübingen, Germany.
²¹ Department of Radiotherapy and Special Oncology, Medical School Hannover, Hannover, Germany.
²² Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany.
²³ Department of Nuclear Medicine, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
²⁴ Department of Radiation Oncology, West German Cancer Centre, University of Duisburg-Essen, Essen, Germany.
²⁵ German Cancer Consortium (DKTK), Partner Site Frankfurt, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
²⁶ Department of Radiotherapy and Oncology, Goethe-University Frankfurt, Frankfurt, Germany.
²⁷ Department of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany.
²⁸ Department of Radiation Oncology, Ulm University Hospital, Ulm, Germany.
²⁹ National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.
³⁰ German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
³¹ Department of Nuclear Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
³² Department of Nuclear Medicine, Klinikum Chemnitz gGmbH, Chemnitz, Germany.
³³ Department of Radiation Oncology, Charité-Universitätsmedizin Berlin, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
³⁴ Section for Biomedical Physics, Department of Radiation Oncology, University of Tübingen, Tübingen, Germany.
³⁵ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. esther.troost@uniklinikum-dresden.de.
³⁶ OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany. esther.troost@uniklinikum-dresden.de.
³⁷ National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany. esther.troost@uniklinikum-dresden.de.
³⁸ German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany. esther.troost@uniklinikum-dresden.de.
³⁹ Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany. esther.troost@uniklinikum-dresden.de.

PMID: 34259912
DOI: 10.1007/s00066-021-01812-2

Review

Value of PET imaging for radiation therapy

Constantin Lapa et al. Strahlenther Onkol. 2021 Sep.

. 2021 Sep;197(9):1-23.

doi: 10.1007/s00066-021-01812-2. Epub 2021 Jul 14.

Authors

Collaborators

Arbeitsgemeinschaft Nuklearmedizin und Strahlentherapie der DEGRO und DGN:
Constantin Lapa, Ursula Nestle, Nathalie L Albert, Christian Baues, Ambros Beer, Andreas Buck, Volker Budach, Rebecca Bütof, Stephanie E Combs, Thorsten Derlin, Matthias Eiber, Wolfgang P Fendler, Christian Furth, Cihan Gani, Eleni Gkika, Anca-L Grosu, Christoph Henkenberens, Harun Ilhan, Steffen Löck, Simone Marnitz-Schulze, Matthias Miederer, Michael Mix, Nils H Nicolay, Maximilian Niyazi, Christoph Pöttgen, Claus M Rödel, Imke Schatka, Sarah M Schwarzenboeck, Andrei S Todica, Wolfgang Weber, Simone Wegen, Thomas Wiegel, Constantinos Zamboglou, Daniel Zips, Klaus Zöphel, Sebastian Zschaeck, Daniela Thorwarth, Esther G C Troost

Affiliations

¹ Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany.
² Department of Radiation Oncology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.
³ German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
⁴ Department of Radiation Oncology, Kliniken Maria Hilf, Mönchengladbach, Germany.
⁵ Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.
⁶ Department of Radiation Oncology, Cyberknife and Radiotherapy, Medical Faculty, University Hospital Cologne, Cologne, Germany.
⁷ Department of Nuclear Medicine, Ulm University Hospital, Ulm, Germany.
⁸ Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
⁹ Department of Radiation Oncology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.
¹⁰ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
¹¹ OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.
¹² German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.
¹³ Department of Radiation Oncology, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
¹⁴ Department of Radiation Sciences (DRS), Institute of Radiation Medicine (IRM), Neuherberg, Germany.
¹⁵ Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
¹⁶ Department of Nuclear Medicine, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
¹⁷ Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
¹⁸ Department of Nuclear Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
¹⁹ German Cancer Consortium (DKTK), Partner Site Tübingen, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
²⁰ Department of Radiation Oncology, University of Tübingen, Tübingen, Germany.
²¹ Department of Radiotherapy and Special Oncology, Medical School Hannover, Hannover, Germany.
²² Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany.
²³ Department of Nuclear Medicine, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
²⁴ Department of Radiation Oncology, West German Cancer Centre, University of Duisburg-Essen, Essen, Germany.
²⁵ German Cancer Consortium (DKTK), Partner Site Frankfurt, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
²⁶ Department of Radiotherapy and Oncology, Goethe-University Frankfurt, Frankfurt, Germany.
²⁷ Department of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany.
²⁸ Department of Radiation Oncology, Ulm University Hospital, Ulm, Germany.
²⁹ National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.
³⁰ German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
³¹ Department of Nuclear Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
³² Department of Nuclear Medicine, Klinikum Chemnitz gGmbH, Chemnitz, Germany.
³³ Department of Radiation Oncology, Charité-Universitätsmedizin Berlin, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
³⁴ Section for Biomedical Physics, Department of Radiation Oncology, University of Tübingen, Tübingen, Germany.
³⁵ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. esther.troost@uniklinikum-dresden.de.
³⁶ OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany. esther.troost@uniklinikum-dresden.de.
³⁷ National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany. esther.troost@uniklinikum-dresden.de.
³⁸ German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany. esther.troost@uniklinikum-dresden.de.
³⁹ Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany. esther.troost@uniklinikum-dresden.de.

PMID: 34259912
DOI: 10.1007/s00066-021-01812-2

Erratum in

Correction to: Value of PET imaging for radiation therapy.
Lapa C, Nestle U, Albert NL, Baues C, Beer A, Buck A, Budach V, Bütof R, Combs SE, Derlin T, Eiber M, Fendler WP, Furth C, Gani C, Gkika E, Grosu AL, Henkenberens C, Ilhan H, Löck S, Marnitz-Schulze S, Miederer M, Mix M, Nicolay NH, Niyazi M, Pöttgen C, Rödel CM, Schatka I, Schwarzenboeck SM, Todica AS, Weber W, Wegen S, Wiegel T, Zamboglou C, Zips D, Zöphel K, Zschaeck S, Thorwarth D, Troost EGC; Arbeitsgemeinschaft Nuklearmedizin und Strahlentherapie der DEGRO und DGN. Lapa C, et al. Strahlenther Onkol. 2022 Jan;198(1):80-82. doi: 10.1007/s00066-021-01851-9. Strahlenther Onkol. 2022. PMID: 34617130 No abstract available.

Abstract

This comprehensive review written by experts in their field gives an overview on the current status of incorporating positron emission tomography (PET) into radiation treatment planning. Moreover, it highlights ongoing studies for treatment individualisation and per-treatment tumour response monitoring for various primary tumours. Novel tracers and image analysis methods are discussed. The authors believe this contribution to be of crucial value for experts in the field as well as for policy makers deciding on the reimbursement of this powerful imaging modality.

Keywords: Functional imaging; PET; Radiation oncology; Radiomics.

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References

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1. Galldiks N, Langen K‑J, Albert NL, Chamberlain M, Soffietti R, Kim MM, Law I, Le Rhun E, Chang S, Schwarting J, Combs SE, Preusser M, Forsyth P, Pope W, Weller M, Tonn JC (2019) PET imaging in patients with brain metastasis—Report of the RANO/PET group. Neuro Oncol 21(5):585–595. https://doi.org/10.1093/neuonc/noz003 - PubMed - PMC

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Value of PET imaging for radiation therapy

Collaborators

Affiliations

Value of PET imaging for radiation therapy

Authors

Collaborators

Affiliations

Erratum in

Abstract

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical