Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2021 Nov 1;40(11):e424-e426.
doi: 10.1097/INF.0000000000003256.

Low Prevalence of Severe Underlying Pathology in Children With Recurrent Respiratory Tract Infections

Daphne Peeters  1 , Pieter Verhulst  2 , Anja Aph Vaessen-Verberne  3 , Xandra W van den Tweel  4 , Jeroen G Noordzij  5 , Gertjan J A Driessen  1   6
Affiliations
Observational Study

Low Prevalence of Severe Underlying Pathology in Children With Recurrent Respiratory Tract Infections

Daphne Peeters et al. Pediatr Infect Dis J. .

Abstract

No underlying pathology could be detected in 64% of 208 children presenting with recurrent respiratory tract infections in general pediatric practice. Asthma/preschool wheezing and adenoid hypertrophy were commonly diagnosed. None of the children had a severe primary immunodeficiency or severe pulmonary illness such as cystic fibrosis. Our findings can guide pediatricians in their diagnostic approach of children with respiratory tract infections.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

References

    1. Principi N, Esposito S, Cavagna R, et al.; Snoopy Study Group. Recurrent respiratory tract infections in pediatric age: a population-based survey of the therapeutic role of macrolides. J Chemother. 2003;15:53–59.
    1. Toivonen L, Karppinen S, Schuez-Havupalo L, et al. Burden of recurrent respiratory tract infections in children: a Prospective Cohort Study. Pediatr Infect Dis J. 2016;35:e362–e369.
    1. Celedon JC, Litonjua AA, Weiss ST, et al. Day care attendance in the first year of life and illnesses of the upper and lower respiratory tract in children with a familial history of atopy. Pediatrics. 1999;104(3 pt 1):495–500.
    1. Nicolai A, Frassanito A, Nenna R, et al. Risk factors for virus-induced acute respiratory tract infections in children younger than 3 years and recurrent wheezing at 36 months follow-up after discharge. Pediatr Infect Dis J. 2017;36:179–183.
    1. Hoving MF, Brand PL. Causes of recurrent pneumonia in children in a general hospital. J Paediatr Child Health. 2013;49:E208–E212.

Publication types

LinkOut - more resources