REPLY

Lukas Otero Sanchez^#^{1

2}, Eleni Karakike^#³, Christophe Moreno^{1

2}, Eric Trépo^{1

2}, Thierry Gustot^{1

2

4

5}

Affiliations

¹ Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, C.U.B. Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
² Laboratory of Experimental Gastroenterology, Université Libre de Bruxelles, Brussels, Belgium.
³ Clinic of Infectious Diseases, CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
⁴ Inserm Unité 1149, Centre de recherche sur l'inflammation, Paris, France.
⁵ UMR S_1149, Université Paris Diderot, Paris, France.

^# Contributed equally.

Comment

Lukas Otero Sanchez et al. Hepatology. 2021 Nov.

. 2021 Nov;74(5):2927-2928.

doi: 10.1002/hep.32057. Epub 2021 Aug 31.

Lukas Otero Sanchez^#^{1

2}, Eleni Karakike^#³, Christophe Moreno^{1

2}, Eric Trépo^{1

2}, Thierry Gustot^{1

2

4

5}

¹ Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, C.U.B. Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
² Laboratory of Experimental Gastroenterology, Université Libre de Bruxelles, Brussels, Belgium.
³ Clinic of Infectious Diseases, CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
⁴ Inserm Unité 1149, Centre de recherche sur l'inflammation, Paris, France.
⁵ UMR S_1149, Université Paris Diderot, Paris, France.

^# Contributed equally.

No abstract available

Comment on

PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis.
Trebicka J, Fernandez J, Papp M, Caraceni P, Laleman W, Gambino C, Giovo I, Uschner FE, Jansen C, Jimenez C, Mookerjee R, Gustot T, Albillos A, Bañares R, Jarcuska P, Steib C, Reiberger T, Acevedo J, Gatti P, Shawcross DL, Zeuzem S, Zipprich A, Piano S, Berg T, Bruns T, Danielsen KV, Coenraad M, Merli M, Stauber R, Zoller H, Ramos JP, Solé C, Soriano G, de Gottardi A, Gronbaek H, Saliba F, Trautwein C, Kani HT, Francque S, Ryder S, Nahon P, Romero-Gomez M, Van Vlierberghe H, Francoz C, Manns M, Garcia-Lopez E, Tufoni M, Amoros A, Pavesi M, Sanchez C, Praktiknjo M, Curto A, Pitarch C, Putignano A, Moreno E, Bernal W, Aguilar F, Clària J, Ponzo P, Vitalis Z, Zaccherini G, Balogh B, Gerbes A, Vargas V, Alessandria C, Bernardi M, Ginès P, Moreau R, Angeli P, Jalan R, Arroyo V; PREDICT STUDY group of the EASL-CLIF CONSORTIUM. Trebicka J, et al. J Hepatol. 2021 May;74(5):1097-1108. doi: 10.1016/j.jhep.2020.11.019. Epub 2020 Nov 20. J Hepatol. 2021. PMID: 33227350
Letter to the Editor: Infections in Severe Forms of Alcohol-Associated Liver Disease: Need a Closer Look!
Jindal A. Jindal A. Hepatology. 2021 Nov;74(5):2926-2927. doi: 10.1002/hep.32058. Epub 2021 Aug 31. Hepatology. 2021. PMID: 34260765 No abstract available.

1. Otero Sanchez L, Karakike E, Njimi H, Putignagno A, Degré D, Hites M, et al. Clinical course and risk factors for infection in severe forms of alcohol-related liver disease. Hepatology 2021 May 28. https://doi.org/10.1002/hep.31984. [Epub ahead of print]
1. Louvet A, Wartel F, Castel H, Dharancy S, Hollebecque A, Canva-Delcambre V, et al. Infection in patients with severe alcoholic hepatitis treated with steroids: early response to therapy is the key factor. Gastroenterology 2009;137:541-548.
1. Thursz MR, Richardson P, Allison M, Austin A, Bowers M, Day CP, et al. Prednisolone or pentoxifylline for alcoholic hepatitis. N Engl J Med 2015;372:1619-1628.
1. Talbot GH, Powers JH, Hoffmann SC; Biomarkers Consortium of the Foundation for the National Institutes of Health CABP-ABSSSI and HABP-VABP Project Teams. Developing outcomes assessments as endpoints for registrational clinical trials of antibacterial drugs: 2015 update from the Biomarkers Consortium of the Foundation for the National Institutes of Health. Clin Infect Dis 2016;62:603-607.
1. Piano S, Bartoletti M, Tonon M, Baldassarre M, Chies G, Romano A, et al. Assessment of sepsis-3 criteria and quick SOFA in patients with cirrhosis and bacterial infections. Gut 2018;67:1892-1899.