Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Sep;22(9):585.
doi: 10.1038/s41580-021-00400-7.

Targeting viruses in their phase

Paulina Strzyz  1
Affiliations
Comment

Targeting viruses in their phase

Paulina Strzyz. Nat Rev Mol Cell Biol. 2021 Sep.

Abstract

The pathogenicity of SARS-CoV-2 and respiratory syncytial virus (RSV) involves mechanisms of liquid–liquid phase separation, which can be explored as targets for new antiviral therapeutics.

PubMed Disclaimer

Figures

None
V. Summersby/Springer Nature Limited
See this image and copyright information in PMC

Comment on

References

Original articles

    1. Wang S, et al. Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity. Nat. Cell Biol. 2021 doi: 10.1038/s41556-021-00710-0. - DOI - PubMed
    1. Risso-Ballester J, et al. A condensate-hardening drug blocks RSV replication in vivo. Nature. 2021 doi: 10.1038/s41586-021-03703-z. - DOI - PubMed

Related article

    1. Lyon AS, Peeples WB, Rosen MK. A framework for understanding the functions of biomolecular condensates across scales. Nat. Rev. Mol. Cell Biol. 2021;22:215–235. doi: 10.1038/s41580-020-00303-z. - DOI - PMC - PubMed

MeSH terms