Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jul 15;11(3).
doi: 10.2106/JBJS.CC.20.00724.

Chondrosarcoma Arising in Synovial Chondromatosis of the Hip: A Case Report

Kelly M Tomasevich  1 , Sara Moradi  2 , Adam D Lindsay  3   4
Affiliations
Case Reports

Chondrosarcoma Arising in Synovial Chondromatosis of the Hip: A Case Report

Kelly M Tomasevich et al. JBJS Case Connect. .

Abstract

Case: Synovial chondromatosis (SC) is a rare condition involving the proliferation of cartilage within the synovial membrane secondary to subsynovial connective tissue metaplasia. Malignant transformation to chondrosarcoma is rare. We cite a case of SC of the hip refractory to arthroscopic debridement, found to have secondary chondrosarcoma on aborted total hip arthroplasty, in which curative treatment was ultimately obtained with external hemipelvectomy.

Conclusion: SC has the potential to undergo malignant transformation to chondrosarcoma. The consequences of not recognizing such transformation can significantly impact patient outcomes and limit options for local control surgery and limb salvage.

PubMed Disclaimer

Conflict of interest statement

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/B598).

References

    1. McCarthy C, Anderson WJ, Vlychou M, Inagaki Y, Whitwell D, Gibbons CL, Athanasou NA. Primary synovial chondromatosis: a reassessment of malignant potential in 155 cases. Skeletal Radiol. 2016;45(6):755-62.
    1. Fuerst M, Zustin J, Lohmann C, Rüther W. Synovial chondromatosis. Orthopade. 2009;38(6):511-9.
    1. McKenzie G, Raby N, Ritchie D. A pictorial review of primary synovial osteochondromatosis. Eur Radiol. 2008;18(11):2662-9.
    1. Lim SJ, Chung HW, Choi YL, Moon YW, Seo JG, Park YS. Operative treatment of primary synovial osteochondromatosis of the hip. J Bone Joint Surg Am. 2006;88(11):2456-64.
    1. Ogilvie-Harris DJ, Saleh K. Generalized synovial chondromatosis of the knee: a comparison of removal of the loose bodies alone with arthroscopic synovectomy. Arthroscopy. 1994;10(2):166-70.

Publication types

MeSH terms

LinkOut - more resources