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Case Reports
. 2022 Jan-Feb;33(1):e19-e21.
doi: 10.1097/SCS.0000000000007861.

Diffuse Large B-Cell Lymphoma Arising in the Lacrimal Sac

Jonghyun Kim  1 , Joohyun Kim, Sehyun Baek
Affiliations
Case Reports

Diffuse Large B-Cell Lymphoma Arising in the Lacrimal Sac

Jonghyun Kim et al. J Craniofac Surg. 2022 Jan-Feb.

Abstract

The authors report a single case of diffuse large B-cell lymphoma arising in the lacrimal sac. Diffuse large B-cell lymphoma is a third most common primary ocular adnexal lymphoma, which is the most common primary ocular malignant disease in adults. A patient came to our clinic with epiphora and a growing mass in the lacrimal sac. Enhanced computed tomography imaging suggested the presence of a malignant tumor and surgical excision and biopsy were performed. A final diagnosis of diffuse large B-cell lymphoma was reached by immunohistological and immunochemical staining. Two months after surgery, diffuse large B-cell lymphoma relapse occurred in the lacrimal sac and the patient underwent 6 cycles of chemotherapy. Diffuse large B-cell lymphoma is a curable disease when diagnosed early, and aggressive biopsy during surgery of the lacrimal sac is necessary to diagnose diffuse large B-cell lymphoma in the early stage. It is important to distinguish diffuse large B-cell lymphoma from other lacrimal system diseases.

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Conflict of interest statement

The authors report no conflicts of interest.

References

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