Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun 18;8(7):002576.
doi: 10.12890/2021_002576. eCollection 2021.

Community-acquired Klebsiella spp Meningitis/Invasive Infection in Filipino-descent Patients Living in Greece: A Case Series

Giorgos Marinakis  1 , Georgios Kassianidis  2 , Eleni Kafkoula  3 , Christina Stamatopoulou  1 , Fotios Kavallieratos  1 , Maria Patrani  1 , Chrysostomos Katsenos  1
Affiliations

Community-acquired Klebsiella spp Meningitis/Invasive Infection in Filipino-descent Patients Living in Greece: A Case Series

Giorgos Marinakis et al. Eur J Case Rep Intern Med. .

Abstract

Klebsiella spp community-acquired meningitis caused by hypervirulent strains is well described as part of a distinct syndrome consisting of liver abscess and multiple septic metastatic lesions (Klebsiella pneumoniae invasive syndrome) occurring usually in diabetic, alcoholic, elderly or cancer patients, in Taiwan and other South-East Asian countries. In Western countries, these infections are very rare in natives and usually occur in patients of Asian origin. We report three cases of Filipino-origin patients, residents of Greece, with community-acquired invasive Klebsiella meningitis, who were treated in our ICU over a 10-year period.

Learning points: Community-acquired Klebsiella spp meningitis has a very bad prognosis.A physician must suspect an invasive Klebsiella infection in patients of Asian origin, even though they are residents of Western countries and have not visited their homeland recently.

Keywords: Meningitis; hypervirulent Klebsiella spp; liver abscess.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interests: The authors declare there are no competing interests.

Figures

Figure 1
Figure 1
CT scan of patient 1 showing a hypodense segment VII liver lesion (abscess) and multiple bile stones
Figure 2
Figure 2
A CT scan of patient 2 showing cavitating pulmonary consolidation
Figure 3
Figure 3
A CT scan of patient 2 showing a hypodense liver lesion compatible with a liver abscess
Figure 4
Figure 4
Cervical CT of patient 3 some 9 months before admission showing a neck abscess. The abscess was successfully drained and the pus culture yielded Klebsiella ozaenae
See this image and copyright information in PMC

References

    1. Chang W-N, Huang C-R, Lu C-H, Chien C-C. Adult Klebsiella pneumoniae meningitis in Taiwan: an overview. Acta Neurol Taiwan. 2012;21(2):87–96. - PubMed
    1. Ku Y-H, Chuang Y-C, Chen C-C, Lee M-F, Yang Y-C, Tang H-J, et al. Klebsiella pneumoniae isolates from meningitis: epidemiology, virulence and antibiotic resistance. Sci Rep. 2017;16:1–10. - PMC - PubMed
    1. Jun J-B. Klebsiella pneumoniae liver abscess. Infect Chemother. 2018;50(3):210–219. - PMC - PubMed
    1. Galani I, Karaiskos I, Karantani I, Papoutsaki V, Maraki S, Papaioannou V, et al. Epidemiology and resistance phenotypes of carbapenemase-producing Klebsiella pneumoniae in Greece, 2014 to 2016. Eurosurveillance. 2018;23(31) - PubMed
    1. Siu LK, Yeh K-M, Lin J-C, Fung C-P, Chang F-Y. Klebsiella pneumoniae liver abscess: a new invasive syndrome. Lancet Infect Dis. 2012;12(11):881–887. - PubMed

LinkOut - more resources