Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2021 Dec;10(1):1515-1518.
doi: 10.1080/22221751.2021.1957402.

The impact of the SARS-CoV-2 pandemic on the prevalence of respiratory tract pathogens in patients with community-acquired pneumonia in Germany

Affiliations
Multicenter Study

The impact of the SARS-CoV-2 pandemic on the prevalence of respiratory tract pathogens in patients with community-acquired pneumonia in Germany

Theo Dähne et al. Emerg Microbes Infect. 2021 Dec.

Abstract

We show a shift in the prevalence of respiratory viral pathogens in community-acquired pneumonia patients during the COVID-19 pandemic. Our data support the efficiency of non-pharmaceutical interventions on virus circulation except for rhinoviruses. The consequences of an altered circulation on subsequent winter seasons remain unclear and support the importance of systematic virological surveillance.

Keywords: SARS-CoV-2; community-acquired pneumonia; molecular methods; prospective study; viral pathogens.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Histogram showing the total number of patients tested positive for a respiratory pathogen (left y-axis) using multiplex real-time RT-PCR per month in 2018 (Panel A), 2019 (Panel B), and 2020 [Panel C, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)]. Black broken line (Influenza virus A/B, RKI) denotes influenza case notifications submitted to the Robert-Koch-Institute, Germany (right y-axis, in log scale). Influenza A/B, RKI numbers were extracted from SurvStat software on 10th March 2021.

References

    1. Jain S, Self WH, Wunderink RG, et al. . Community-acquired pneumonia requiring hospitalization. N Engl J Med. 2015 Dec 10;373(24):2382. - PMC - PubMed
    1. Das D, Le Floch H, Houhou N, et al. . Viruses detected by systematic multiplex polymerase chain reaction in adults with suspected community-acquired pneumonia attending emergency departments in France. Clin Microbiol Infect. 2015 Jun;21(6):608 e1–8. - PMC - PubMed
    1. Hsiang S, Allen D, Annan-Phan S, et al. . The effect of large-scale anti-contagion policies on the COVID-19 pandemic. Nature. 2020 Aug;584(7820):262–267. - PubMed
    1. Sullivan SG, Carlson S, Cheng AC, et al. . Where has all the influenza gone? The Impact of COVID; 19, on the circulation of influenza and other respiratory viruses, Australia, March to September 2020. Euro Surveill. 2020 Nov;25(47). - PMC - PubMed
    1. Panning M, Wiener J, Rothe K, et al. . No SARS-CoV-2 detection in the German CAPNETZ cohort of community acquired pneumonia before COVID-19 peak in march 2020. Infection. 2020 Dec;48(6):971–974. - PMC - PubMed

MeSH terms