Comment
doi: 10.1016/j.plrev.2021.06.001.
Epub 2021 Jun 29.
Information-theoretic characterization of the complete genotype-phenotype map of a complex pre-biotic world: Comment on "From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics" by Susanna Manrubia et al
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- PMID: 34272193
- DOI: 10.1016/j.plrev.2021.06.001
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Comment
Information-theoretic characterization of the complete genotype-phenotype map of a complex pre-biotic world: Comment on "From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics" by Susanna Manrubia et al
Phys Life Rev.
2021 Sep.
Abstract
How information is encoded in bio-molecular sequences is difficult to quantify since such an analysis usually requires sampling an exponentially large genetic space. Here we show how information theory reveals both robust and compressed encodings in the largest complete genotype-phenotype map (over 5 trillion sequences) obtained to date.
Copyright © 2021 Elsevier B.V. All rights reserved.
Conflict of interest statement
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Comment on
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From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics.Phys Life Rev. 2021 Sep;38:55-106. doi: 10.1016/j.plrev.2021.03.004. Epub 2021 May 21. Phys Life Rev. 2021. PMID: 34088608 Review.
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