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Review
. 2021 Jul 17;38(8):97.
doi: 10.1007/s12032-021-01548-0.

Resveratrol effects in oral cancer cells: a comprehensive review

Tamires Cunha Almeida  1 , Glenda Nicioli da Silva  1 , Daniel Vitor de Souza  2 , Andrea Cristina de Moraes Malinverni  3 , Odair Aguiar Jr  2 , Debora Estadella  2 , Daniel Araki Ribeiro  4
Affiliations
Review

Resveratrol effects in oral cancer cells: a comprehensive review

Tamires Cunha Almeida et al. Med Oncol. .

Abstract

Oral cancer is a very common tumor worldwide with high incidence and mortality. The treatment of oral cancer involves surgery, radio- and chemotherapy; however, high failure rates and toxicity are noticed. Thus, the search of new drugs aiming a more effective treatment is welcomed. Natural products present chemopreventive and anti-cancer effects. Resveratrol is a naturally occurring antioxidant that contains several health benefits, including anti-inflammatory and antiproliferative activities. This review discusses the different action mechanisms of resveratrol related in the in vitro and in vivo studies using models of oral cancer.

Keywords: In vitro; In vivo; Oral cancer; Resveratrol.

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