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Review
. 2021 Sep:264:21-24.
doi: 10.1016/j.ejogrb.2021.07.002. Epub 2021 Jul 7.

Catastrophic antiphospholipid syndrome during pregnancy

Marta Fuentes Carrasco  1 , Alejandra Mayoral Triana  2 , Ignacio Cristóbal Cristóbal García  3 , Noelia Pérez Pérez  2 , Nuria Izquierdo Méndez  4 , Patricia Soler Ruiz  4 , Virginia González González  2
Affiliations
Review

Catastrophic antiphospholipid syndrome during pregnancy

Marta Fuentes Carrasco et al. Eur J Obstet Gynecol Reprod Biol. 2021 Sep.

Abstract

Catastrophic antiphospholipid syndrome (CAPS) is an uncommon and the most severe form of antiphospholipid syndrome (APS). A 33-week pregnant patient with Klippel-Trenaunay syndrome, past SARS-CoV-2 infection and type I fetal growth restriction with shortening of the fetal long bone was diagnosed in our center with a probable CAPS. Cesarean section was performed four days after the diagnosis due to the torpid evolution of the patient. Clinical improvement was noted a few days later and the mother and baby were discharged within a week. We review the current literature on CAPS during pregnancy and provide an updated view.

Keywords: Antiphospholipid syndrome; Catastrophic antiphospholipid syndrome; Fetal growth restriction; Klippel-Trenaunay syndrome; Pregnancy; SARS-CoV-2.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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