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. 2022 Mar;32(3):506-507.
doi: 10.1017/S1047951121003280. Epub 2021 Jul 19.

Kawasaki disease shock syndrome in the COVID-19 pandemic

Luisa B Gámez-González  1 , Moises J Ramírez-López  2 , Marcela Colmenero-Rascón  3 , Marco A Yamazaki-Nakashimada  4
Affiliations

Kawasaki disease shock syndrome in the COVID-19 pandemic

Luisa B Gámez-González et al. Cardiol Young. 2022 Mar.

Abstract

Multisystem inflammatory syndrome in children is a new entity in association with SARS-CoV2. Clinical features of Kawasaki disease were noted from the first reported cases of MIS-C. Before the COVID-19 pandemic, Kawasaki disease shock syndrome was considered to be a distinct and unique form of KD. We present a representative case that prove the current difficulty in clearly distinguishing MIS-C from pre-COVID-19-KDSS and emphasie the overlap of the diagnostic criteria.

Keywords: COVID-19; Kawasaki disease; Kawasaki disease shock syndrome; SARS-CoV2; multisystem inflammatory syndrome in children.

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References

    1. Whittaker E, Bamford A, Kenny J, et al.Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 2020; 324: 259–269. DOI: 10.1001/jama.2020.10369. - DOI - PMC - PubMed
    1. Gardner-Medwin JM, Dolezalova P, Cummins C, Southwood TR.Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 2002; 360: 1197–1202. DOI: 10.1016/S0140-6736(02)11279-7. - DOI - PubMed
    1. Kanegaye JT, Wilder MS, Molkara D, et al.Recognition of a Kawasaki disease shock syndrome. Pediatrics 2009; 123: e783–e789. - PMC - PubMed
    1. Gamez-Gonzalez LB, Moribe-Quintero I, Cisneros-Castolo M, et al.Kawasaki disease shock syndrome: unique and severe subtype of Kawasaki disease. Pediatr Int 2018; 60: 781–790. - PubMed
    1. Noval Rivas M, Porritt RA, Cheng MH, Bahar I, Arditi M.COVID-19-associated multisystem inflammatory syndrome in children (MIS-C): a novel disease that mimics toxic shock syndrome the superantigen hypothesis. J Allergy Clin Immunol 2021; 147: 57–59. DOI: 10.1016/j.jaci.2020.10.008. - DOI - PMC - PubMed

Supplementary concepts