Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2022 May-Jun;16(3):303-309.
doi: 10.1097/ADM.0000000000000892.

The Prognostic Role of DSM-5 Alcohol Use Disorder Severity and Age of Onset in Treatment Outcome Among Adults Aged 60

Silke Behrendt  1 , Alexis Kuerbis, Anna Mejldal, Barbara Braun-Michl, Randi Bilberg, Gerhard Bu Hringer, Michael Bogenschutz, Anette Søgaard Nielsen, Kjeld Andersen
Affiliations
Multicenter Study

The Prognostic Role of DSM-5 Alcohol Use Disorder Severity and Age of Onset in Treatment Outcome Among Adults Aged 60

Silke Behrendt et al. J Addict Med. 2022 May-Jun.

Abstract

Aims: To investigate among older adults with DSM-5 alcohol use disorder (AUD) the relevance of (1) baseline DSM-5 AUD severity, (2) age of DSM-5 AUD onset, and (3) the interactions of DSM-5 AUD severity*treatment condition and age of DSM-5 AUD onset*treatment condition for the prediction of AUD treatment outcomes.

Methods: The international multicenter RCT "ELDERLY-Study" compared outpatient motivational enhancement therapy (4 sessions) with outpatient motivational enhancement therapy followed by community reinforcement approach for seniors (8 sessions) in adults aged 60+ with DSM-5 AUD. Baseline and 1-, 3-, and 6-month follow-up data from the German and Danish ELDERLY-sites (n = 544) were used (6-month participation rate: 75.9%). DSM-5 AUD diagnoses were obtained using the Mini International Neuropsychiatric Interview and alcohol use using Form 90. Associations between DSM-5 AUD severity and age of onset and AUD treatment outcomes were investigated using multiple logistic regression and generalized linear models.

Results: The sample was diverse in AUD severity (severe: 54.9%, moderate: 28.2%, mild: 16.9%) and age of onset (median: 50 years; 12-78 years). Overall, with few exceptions, neither AUD severity, nor age of onset, nor their respective interactions with treatment condition significantly predicted drinking outcomes at the different follow-ups ( P ≥ 0.05).

Conclusions: No indication was found for the need to tailor treatment content according to DSM-5 AUD severity and earlier onset in older adults.

Trial registration: ClinicalTrials.gov NCT02084173.

PubMed Disclaimer

Conflict of interest statement

The other authors report no conflicts of interest.

Similar articles

See all similar articles

Cited by

References

    1. Han BH, Moore AA, Sherman S, et al. Demographic trends of binge alcohol use and alcohol use disorders among older adults in the United States, 2005-2014. Drug Alcohol Depend . 2017;170:198–207.
    1. Grant BF, Goldstein RB, Saha TD, et al. Epidemiology of DSM-5 alcohol use disorder results from the national epidemiologic survey on alcohol and related conditions III. JAMA Psychiatry . 2015;72(8):757–766.
    1. Adamson SJ, Sellman JD, Frampton CMA. Patient predictors of alcohol treatment outcome: A systematic review. J Subst Abuse Treat . 2009;36(1):75–86.
    1. Kuerbis A, Sacco P. The impact of retirement on the drinking patterns of older adults: A review. Addict Behav . 2012;37(5):587–595.
    1. Caputo F, Vignoli T, Leggio L, et al. Alcohol use disorders in the elderly: A brief overview from epidemiology to treatment options. Exp Gerontol . 2012;47(6):411–416.

Publication types

Associated data