Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul 20;73(1):67.
doi: 10.1186/s43044-021-00189-y.

Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)

Affiliations

Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)

Hesham Bahaa et al. Egypt Heart J. .

Abstract

Background: Transcatheter aortic valve implantation (TAVI) is a well-established and standard therapy for patients with symptomatic severe aortic stenosis at moderate or high risk for surgical aortic valve replacement. Recently, it has proven non-inferior in patients with low surgical risk. However, due to its high cost, the availability of TAVI is variable worldwide. Our aim was to assess the demographic and clinical characteristics and short-term and long-term outcome of those patients. A medical registry is believed to be an excellent tool to perform a field analysis of patients' course, documenting short, intermediate, and long-term outcomes. This is the first registry for patients who underwent TAVI in Egypt.

Results: Ninety-six patients were included in the study; some were retrospective, and the majority were prospective from 5 different cardiac centers from August 2012 till December 2017. The mean age of patients was 77 years SD ± 7.29; females were 52% of the patients and most of the patients were overweight (BMI 30.74, SD ± 6.83). Sixty-three percent of the patients were frail with Katz index ≤ 5. 3.5% had atrial fibrillation (AF) at presentation. General anesthesia was conducted in only 59.37% of the patients. Transfemoral access was the prevailing route of implantation (90%). The median hospital stay was 4 days. In-hospital and 30 days mortality was only 4.16%.

Conclusion: TAVI outcome in Egypt appeared to be very promising with in-hospital complication, and mortality rates being comparable to international registries (4.16% vs. 4.0% in TVT registry) denoting the procedure as safe and beneficial. Establishing a national registry is critical to highlighting strength and weaknesses as well as identifying key areas for improvements.

Keywords: Aortic stenosis; Egy-TVR; Egyptian; Registry; TAVI; Transcatheter aortic valve implantation; Transcatheter valve registry.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Centers contribution. (1) Aswan Heart Centre, Magdi Yacoub Foundation; (2) Galaa Military Hospital Magdi Yacoub Foundation Unit; (3) Ain Shams University Hospital; (4) Dar El fouad, October city; and (5) Andalusia Hospital
Fig. 2
Fig. 2
TAVI procedures across the years
Fig. 3
Fig. 3
Different valves used in the study. The colors in the legend represent the sizes of the valves provided by manufacturer
Fig. 4
Fig. 4
NYHA comparison pre TAVI and post TAVI
Fig. 5
Fig. 5
Pressure gradient follow-up

References

    1. Ross J, Jr, Braunwald E. Aortic stenosis. Circulation. 1968;38(1):61–67. - PubMed
    1. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med. 2010;363(17):1597–1607. doi: 10.1056/NEJMoa1008232. - DOI - PubMed
    1. Cribier A, Eltchaninoff H, Bash A, Borenstein N, Tron C, Bauer F, Derumeaux G, Anselme F, Laborde F̧, Leon MB. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis. Circulation. 2002;106(24):3006–3008. doi: 10.1161/01.CIR.0000047200.36165.B8. - DOI - PubMed
    1. Thaden JJ, Nkomo VT, Enriquez-Sarano M. The global burden of aortic stenosis. Progress in cardiovascular diseases [Internet]. 2014;56(6):565–71. Available from: 10.1016/j.pcad.2014.02.006 - PubMed
    1. Mack MJ, Leon MB, Thourani VH, Makkar R, Kodali SK, Russo M, Kapadia SR, Malaisrie SC, Cohen DJ, Pibarot P, Leipsic J, Hahn RT, Blanke P, Williams MR, McCabe JM, Brown DL, Babaliaros V, Goldman S, Szeto WY, Genereux P, Pershad A, Pocock SJ, Alu MC, Webb JG, Smith CR. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med. 2019;380(18):1695–1705. doi: 10.1056/NEJMoa1814052. - DOI - PubMed

LinkOut - more resources