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Book

Exercise-Associated Hyponatremia

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Exercise-Associated Hyponatremia

Emily Buck et al.
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Excerpt

Exercise-associated hyponatremia (EAH) is defined as a serum sodium level below 135 mmol/L that develops during or up to 24 hours after physical activity. EAH was previously thought to occur only in extreme endurance athletes; however, its incidence is increasing among various athletes presenting with a wide spectrum of symptoms.

Prompt differentiation of EAH from other exertional illnesses is critical, as isotonic fluid administration that may be given for other exertional diagnoses can worsen EAH, resulting in life-threatening sequelae of hyponatremia. EAH is treated with fluid restriction or sodium replacement, depending upon severity. Avoiding overhydration can prevent EAH. Athletes, coaches, healthcare providers, and athletic event staff must be educated on EAH prevention strategies and presenting symptoms to decrease athletes’ risk of development and progression to hyponatremic encephalopathy, coma, or death.

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Conflict of interest statement

Disclosure: Emily Buck declares no relevant financial relationships with ineligible companies.

Disclosure: Rebecca McAllister declares no relevant financial relationships with ineligible companies.

Disclosure: Jeremy Schroeder declares no relevant financial relationships with ineligible companies.

References

    1. Hew-Butler T. Exercise-Associated Hyponatremia. Front Horm Res. 2019;52:178-189. - PubMed
    1. Bennett BL, Hew-Butler T, Rosner MH, Myers T, Lipman GS. Wilderness Medical Society Clinical Practice Guidelines for the Management of Exercise-Associated Hyponatremia: 2019 Update. Wilderness Environ Med. 2020 Mar;31(1):50-62. - PubMed
    1. Oh RC, Galer M, Bursey MM. Found in the Field - A Soldier With Heat Stroke, Exercise-Associated Hyponatremia, and Kidney Injury. Curr Sports Med Rep. 2018 Apr;17(4):123-125. - PubMed
    1. Rosner MH. EXERCISE-ASSOCIATED HYPONATREMIA. Trans Am Clin Climatol Assoc. 2019;130:76-87. - PMC - PubMed
    1. Bridges E, Altherwi T, Correa JA, Hew-Butler T. Oral Hypertonic Saline Is Effective in Reversing Acute Mild-to-Moderate Symptomatic Exercise-Associated Hyponatremia. Clin J Sport Med. 2020 Jan;30(1):8-13. - PubMed

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