Exercise-Associated Hyponatremia
- PMID: 34283494
- Bookshelf ID: NBK572128
Exercise-Associated Hyponatremia
Excerpt
Exercise-associated hyponatremia (EAH) is defined as a serum sodium level below 135 mmol/L that develops during or up to 24 hours after physical activity. EAH was previously thought to occur only in extreme endurance athletes; however, its incidence is increasing among various athletes presenting with a wide spectrum of symptoms.
Prompt differentiation of EAH from other exertional illnesses is critical, as isotonic fluid administration that may be given for other exertional diagnoses can worsen EAH, resulting in life-threatening sequelae of hyponatremia. EAH is treated with fluid restriction or sodium replacement, depending upon severity. Avoiding overhydration can prevent EAH. Athletes, coaches, healthcare providers, and athletic event staff must be educated on EAH prevention strategies and presenting symptoms to decrease athletes’ risk of development and progression to hyponatremic encephalopathy, coma, or death.
Copyright © 2025, StatPearls Publishing LLC.
Conflict of interest statement
Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Prognosis
- Complications
- Consultations
- Deterrence and Patient Education
- Pearls and Other Issues
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
-
- Hew-Butler T. Exercise-Associated Hyponatremia. Front Horm Res. 2019;52:178-189. - PubMed
-
- Bennett BL, Hew-Butler T, Rosner MH, Myers T, Lipman GS. Wilderness Medical Society Clinical Practice Guidelines for the Management of Exercise-Associated Hyponatremia: 2019 Update. Wilderness Environ Med. 2020 Mar;31(1):50-62. - PubMed
-
- Oh RC, Galer M, Bursey MM. Found in the Field - A Soldier With Heat Stroke, Exercise-Associated Hyponatremia, and Kidney Injury. Curr Sports Med Rep. 2018 Apr;17(4):123-125. - PubMed
-
- Bridges E, Altherwi T, Correa JA, Hew-Butler T. Oral Hypertonic Saline Is Effective in Reversing Acute Mild-to-Moderate Symptomatic Exercise-Associated Hyponatremia. Clin J Sport Med. 2020 Jan;30(1):8-13. - PubMed
Publication types
LinkOut - more resources
Full Text Sources