Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Nov-Dec;37(6):e208-e209.
doi: 10.1097/IOP.0000000000002019.

Epibulbar Subconjunctival Apocrine Hidrocystoma

Norman C Charles  1   2 , Leela V Raju  1 , Eleanore T Kim  1
Affiliations
Case Reports

Epibulbar Subconjunctival Apocrine Hidrocystoma

Norman C Charles et al. Ophthalmic Plast Reconstr Surg. 2021 Nov-Dec.

Abstract

Apocrine hidrocystomas are benign cystic tumors derived from apocrine sweat glands; they are most commonly located in the skin of the head and neck regions. Ophthalmic occurrences characteristically appear at the lash line and canthi of the eyelid, although rare instances have been described in the conjunctiva, caruncle, and orbit. The authors describe an exceptional instance of a mobile epibulbar subconjunctival apocrine hidrocystoma in a 57-year-old woman without a history of previous ocular injury or surgery. Histopathology of the excised specimen displayed an empty cyst lined by a double layer of cuboidal epithelium with the inner layer exhibiting periodic acid-Schiff-positive apical decapitation secretion. Confirmatory immunohistochemistry included reactivity with cytokeratin-7, smooth muscle actin, D2-40, and CDGFP-15.

PubMed Disclaimer

Conflict of interest statement

The authors have no financial or conflicts of interest to disclose.

References

    1. Jakobiec FA, Zakka FR. A reappraisal of eyelid eccrine and apocrine hidrocystomas: microanatomic and immunohistochemical studies of 40 lesions. Am J Ophthalmol. 2011;151:358–374.e2.
    1. Kim B, Kang NY. Apocrine hidrocystoma of the conjunctiva. Int J Ophthalmol. 2012;5:247–248.
    1. Luthra CL, Doxanas MT, Green WR. Lesions of the caruncle: a clinicohistopathologic study. Surv Ophthalmol. 1978;23:183–195.
    1. Jakobiec FA, Stacy RC, Colby KA. Pigmented apocrine hidrocystoma of the caruncle. Cornea. 2010;29:1320–1322.
    1. Jakobiec FA, Stagner AM, Colby KA. Pigmented caruncular apocrine hidrocystoma with oncocytic features. Ophthalmic Plast Reconstr Surg. 2017;33(3S Suppl 1):42–45.

Publication types