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Case Reports
. 2021 Jul 20;14(7):e241460.
doi: 10.1136/bcr-2020-241460.

Larynx lymphoepithelial carcinoma: surgical management

Cosimo Galletti  1 , Cristina Pizzimenti  2 , Vittorio Cavallari  2 , Bruno Galletti  3
Affiliations
Case Reports

Larynx lymphoepithelial carcinoma: surgical management

Cosimo Galletti et al. BMJ Case Rep. .

Abstract

Lymphoepithelial carcinoma (LEC) is an entity mostly frequent in the nasopharynx, which represents 40% of all neoplasms. The incidence's not exclusive of a geographic area; however, it has an endemic distribution in Southeast Asia and Eskimos. LEC is not exclusive of the nasopharynx, has also been reported in other anatomical areas, such as the sinonasal tract, nasolacrimal duct, oral cavity, oropharynx, salivary glands, thymus, hypopharynx, oesophagus, stomach, trachea, lung and others. Non-nasopharyngeal and nasopharyngeal LEC have the same microscopic features, but the nasopharyngeal is more likely associated with Epstein-Barr virus. LEC has been approved by the WHO. LEC located in the larynx is quite rare and worthy of attention for its implication in the treatment and prognosis. We present a case of LEC treated in our ENT department in a middle-aged man.

Keywords: ear; head and neck cancer; nose and throat/otolaryngology; otolaryngology / ENT.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Rhinofibrolaryngoscopy shows nonulcerated exofitic neoformation that extended from false right vocal fold to ipsilateral glottis preventing vision of ipsilateral vocal fold.
Figure 2
Figure 2
CT with MDC head and neck: shows contrasting impregnation, extends ventrally to the anterior commissure, infiltrating the ventral third of the contralateral false vocal cord, caudally it infiltrates the ventral half of the true ipsilateral vocal cord and commissure. No signs of thyroid infiltration. Another pseudonodular component in the right paramedian site with partial obliteration of the pre-epiglottic extended to the epiglottic ligament. A 3 cm laryngocele is present on the Morgagni’s ventricle. Several aspecifics lymphadenopathies<1 cm are presented.
Figure 3
Figure 3
(A) Important lymphocitary infiltrated that is suggested lymphoepithelial carcinoma. (B) Important CD4 infiltrated.
Figure 4
Figure 4
Larynx resection.
See this image and copyright information in PMC

References

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