Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Aug;596(7870):38-40.
doi: 10.1038/d41586-021-01962-4.

Private immune protection at the border of the central nervous system

Comment

Private immune protection at the border of the central nervous system

Britta Engelhardt. Nature. 2021 Aug.
No abstract available

Keywords: Brain; Immunology.

PubMed Disclaimer

Comment on

  • Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma.
    Cugurra A, Mamuladze T, Rustenhoven J, Dykstra T, Beroshvili G, Greenberg ZJ, Baker W, Papadopoulos Z, Drieu A, Blackburn S, Kanamori M, Brioschi S, Herz J, Schuettpelz LG, Colonna M, Smirnov I, Kipnis J. Cugurra A, et al. Science. 2021 Jul 23;373(6553):eabf7844. doi: 10.1126/science.abf7844. Epub 2021 Jun 3. Science. 2021. PMID: 34083447 Free PMC article.
  • Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
    Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.

References

    1. Engelhardt, B., Vajkoczy, P. & Weller, R. O. Nature Immunol. 18, 123–131 (2017). - PubMed - DOI
    1. Cugurra, A. et al. Science https://doi.org/10.1126/science.abf7844 (2021). - PubMed
    1. Brioschi, S. et al. Science https://doi.org/10.1126/science.abf9277 (2021). - PubMed
    1. Rua, R. & McGavern, D. B. Trends Mol. Med. 24, 542–559 (2018). - PubMed - DOI - PMC
    1. Mrdjen, D. et al. Immunity 48, 599 (2018). - PubMed - DOI