Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Jul;129(7):71303.
doi: 10.1289/EHP9507. Epub 2021 Jul 21.

Invited Perspective: Prioritizing Chemical Testing and Evaluation Using Validated in Vitro Assays Relevant to Key Characteristics

Kathryn Z Guyton  1 , Mary K Schubauer-Berigan  1
Affiliations
Comment

Invited Perspective: Prioritizing Chemical Testing and Evaluation Using Validated in Vitro Assays Relevant to Key Characteristics

Kathryn Z Guyton et al. Environ Health Perspect. 2021 Jul.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Arzuaga X, Smith MT, Gibbons CF, Skakkebæk NE, Yost EE, Beverly BEJ, et al. 2019. Proposed key characteristics of male reproductive toxicants as an approach for organizing and evaluating mechanistic evidence in human health hazard assessments. Environ Health Perspect 127(6):65001, PMID: 31199676, 10.1289/EHP5045. - DOI - PMC - PubMed
    1. Cardona B, Rudel R. 2021. Application of an in vitro assay to identify chemicals that increase estradiol and progesterone synthesis and are potential breast cancer risk factors. Environ Health Perspect 129(7):077003, 10.1289/EHP8608. - DOI - PMC - PubMed
    1. Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M, et al. 2021. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. https://gco.iarc.fr/today [accessed 14 April 2021].
    1. Haggard DE, Karmaus AL, Martin MT, Judson RS, Setzer RW, Paul Friedman K. 2018. High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis. Toxicol Sci 162(2):509–534, PMID: 29216406, 10.1093/toxsci/kfx274. - DOI - PMC - PubMed
    1. IARC (International Agency for Research on Cancer). Preamble to the IARC Monographs. 2019. Lyon, France: International Agency for Research on Cancer. https://monographs.iarc.who.int/wp-content/uploads/2019/07/Preamble-2019.... [accessed 14 April 2021].

MeSH terms

LinkOut - more resources