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. 2021 Aug;27(8):2187-2191.
doi: 10.3201/eid2708.204502.

Natural Human Infections with Plasmodium cynomolgi, P. inui, and 4 other Simian Malaria Parasites, Malaysia

Nan Jiun Yap, Hanisah Hossain, Thamayanthi Nada-Raja, Romano Ngui, Azdayanti Muslim, Boon-Peng Hoh, Loke Tim Khaw, Khamisah Abdul Kadir, Paul Cliff Simon Divis, Indra Vythilingam, Balbir Singh, Yvonne Ai-Lian Lim

Natural Human Infections with Plasmodium cynomolgi, P. inui, and 4 other Simian Malaria Parasites, Malaysia

Nan Jiun Yap et al. Emerg Infect Dis. 2021 Aug.

Abstract

We detected the simian malaria parasites Plasmodium knowlesi, P. cynomolgi, P. inui, P. coatneyi, P. inui-like, and P. simiovale among forest fringe-living indigenous communities from various locations in Malaysia. Our findings underscore the importance of using molecular tools to identify newly emergent malaria parasites in humans.

Keywords: Malaysia; Plasmodium; Plasmodium cynomolgi; Plasmodium inui; malaria; parasites; simian; zoonoses.

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Figures

Figure 1
Figure 1
Neighbor-joining phylogenetic tree of Plasmodium species based on partial sequence of SSU rRNA genes for identification of Plasmodium malaria species from indigenous community blood samples, Malaysia. Nucleotide sequences generated from this study are marked with asterisks and are in bold. GenBank accession numbers are provided for all sequences. Numbers at nodes indicate percentage support of 1,000 bootstrap replicates; only bootstrap values above 70% are displayed. Scale bar indicates branch length.
Figure 2
Figure 2
Neighbor-joining phylogenetic tree of Plasmodium species based on partial sequence of COX1 genes for identification of Plasmodium malaria species from indigenous community blood samples, Malaysia. Nucleotide sequences generated from this study are marked with asterisks and are in bold. GenBank accession numbers are provided for all sequences. Numbers at nodes indicate percentage support of 1,000 bootstrap replicates; only bootstrap values above 70% are displayed. Scale bar indicates branch length.
See this image and copyright information in PMC

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